Effectiveness of Pulpotomy in Carious First Permanent Molar

Status Not yet recruiting

Clinical Trial Summary

Clinical Trial Description

Pediatric dentists frequently encounter deeply carious young permanent first molars (PFM) with Molar Incisor Hypomineralisation (MIH). Pulpal status of affected PFM was found to be different from that of unaffected PFMs which consequently might influence the pulpal response after vital pulp therapy. The aim of this study is to evaluate the clinical and radiographic effectiveness of partial removal of pulp in deeply carious symptomatic PFM affected with MIH over 24 months. In this prospective randomized controlled clinical trial, a randomized assigned sample of 96 children each with a deeply carious young PFM, Group I (n=48) diagnosed with MIH and irreversible pulpitis and Group II (n=48) diagnosed with irreversible pulpitis but not affected with MIH. Group I will be randomly equally allocated into Group II A (n=24): partial pulpotomy (PP) and Group I B (n=24): full pulpotomy (FP). Group II will also be randomly equally allocated into Group II A (n=24): PP and Group II B (n=24): FP. If pulpal bleeding cannot be controlled within 6 minutes using cotton pellets soaked in 3% sodium hypochlorite, the allocated procedure will be abandoned. The pulpotomy agent to be used will be mineral trioxide aggregate (MTA) and teeth will be restored using a resin modified glass ionomer restoration (RMGIC). Teeth will be followed up clinically and radiographically using periapical x-rays for 24 months. Cone beam computed tomographic scans will be taken initially and at 24 months. Pain levels will be scored preoperatively before local anesthetic administration and postoperatively every 24 hours for 7 days using visual analogue scale. All data will be statistically analyzed and discussed considering the results obtained. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06137391
Study type	Interventional
Source	Alexandria University
Contact	Rodaina H. Helmy
Phone	+201100001193
Email	rodaina.helmy@alexu.edu.eg
Status	Not yet recruiting
Phase	N/A
Start date	January 2024
Completion date	December 2025

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05485662` - Remineralization of Molar Incisor Hypomineralization (MIH) With a Hydroxyapatite Toothpaste	N/A
Not yet recruiting	`NCT06342089` - Association Between Molar Incisor Hypomineralization And Type I Diabetes Milletus.
Not yet recruiting	`NCT06081491` - Association Between Molar-Incisor Hypomineralization, Maternal Stress and Anxiety: A Cross-Sectional Study.
Not yet recruiting	`NCT04410172` - Prevalence of MIH Among Group of Egyptians Children Aged From 8 to 12 in Damietta
Not yet recruiting	`NCT04030936` - Knowledge Regarding Diagnosis of MIH Among Dental Interns in Faculty of Dentistry Cairo University
Not yet recruiting	`NCT04420520` - Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Fayoum Governorate Schools
Active, not recruiting	`NCT05597956` - Effectiveness of Infiltration With Resin in Treatment of MIH Incisors in Children Showing Opacities	N/A
Completed	`NCT04231019` - Knowledge of Egyptian Dental Practitioners Regarding Molar-Incisor Hypomineralization
Completed	`NCT03735069` - Vital Pulp Therapy in Carious Teeth With Hypomineralization	N/A
Completed	`NCT05494749` - Zirconia Reinforced Glass Ionomer in MIH	N/A
Completed	`NCT05931822` - Silver Diamine Fluoride Modified Restoration In Treating Hypomineralized First Permanent Molar.	N/A
Not yet recruiting	`NCT04475419` - Restoration Quality in Molars Affected by Molar Incisor Hypo Mineralization	N/A
Completed	`NCT04061096` - Local Anesthesia in Molar Teeth With Molar Incisor Hypomineralization	N/A
Active, not recruiting	`NCT05748067` - Minimally Invasive Treatment for Permanent Molars Affected With Molar-incisor Hypomineralization Defects	N/A
Not yet recruiting	`NCT03583671` - Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children From 8 to 12 Years Old in Dakahlia
Active, not recruiting	`NCT03870958` - Glass Ionomer Cement Sealant in the Prevention of Post-eruptive Fractures in Molars Affected by MIH	N/A
Completed	`NCT05727475` - Change in OHRQOL Following Minimally Invasive Treatment of Anterior Teeth in Children With MIH	N/A
Completed	`NCT04685889` - Resin Infiltration Treatment for MIH	N/A
Not yet recruiting	`NCT06330272` - Accuracy of Spectrophotometry in Hypomineralized Lesions Treated With CPP-ACPF Dental Mousse: Clinical Study	N/A
Enrolling by invitation	`NCT03233464` - Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Giza Governorate	N/A