Association Between Molar-Incisor Hypomineralization, Maternal Stress &

Status Not yet recruiting

Clinical Trial Summary

This study aims to evaluate the association between Molar-Incisor Hypomineralization, Maternal Stress and anxiety in a group of pediatric patients.

Clinical Trial Description

Molar incisor hypomineralization is a medical global condition characterised by a qualitative defect in the enamel mineralization affecting the first permanent molar teeth predominantly, and with or without the involvement of incisor teeth. MIH have various and major clinical challenges. Clinically the lesion appears with well demarcated opacity and porous with a color that ranges from white, creamy or yellow to brownish. Thus differ in its severity from mild to severe. The OHRQoL is a fundamental part of our children's general health and well-being but with the condition mentioned above their eating, sleeping, social interaction, self-esteem is being minimized and so the analysis of the etiological factors should be carried out. Worldwide the prevalence of this condition, MIH was found to be from 2.4 to 40%, the reason behind this huge range difference is the use of different indices, diagnostic criteria, variability between examiners, lack of standardized methods of recording lesions and different age groups, while recent studies in Egypt reported 2.3% of MIH in a group of Egyptian children from 8 to 12 years in Cairo. Moreover, 878 million people across the world were MIH-affected and 17.5 million new cases are identified each year according to a study published 02 August 2022 in Egypt. Despite the worldwide increasing interest in the causes of MIH, there is still insufficient evidence to verify the etiological factors of this condition, especially stress and anxiety. There is a potential relationship between stress and MIH, as glucocorticoids mainly cortisol have receptors on ameloblasts and so further research and population-based studies are urgently required to evaluate the prevalence of MIH and its association with stress. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06081491
Study type	Observational
Source	Cairo University
Contact	Sarah M Sadek, bachelor
Phone	01143342788
Email	sarah.sadek@dentistry.cu.edu.eg
Status	Not yet recruiting
Phase
Start date	September 2024
Completion date	October 2025

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See also
Status	Clinical Trial	Phase
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Not yet recruiting	`NCT04410172` - Prevalence of MIH Among Group of Egyptians Children Aged From 8 to 12 in Damietta
Not yet recruiting	`NCT04030936` - Knowledge Regarding Diagnosis of MIH Among Dental Interns in Faculty of Dentistry Cairo University
Not yet recruiting	`NCT04420520` - Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Fayoum Governorate Schools
Recruiting	`NCT05597956` - Effectiveness of Infiltration With Resin in Treatment of MIH Incisors in Children Showing Opacities	N/A
Completed	`NCT04231019` - Knowledge of Egyptian Dental Practitioners Regarding Molar-Incisor Hypomineralization
Completed	`NCT03735069` - Vital Pulp Therapy in Carious Teeth With Hypomineralization	N/A
Completed	`NCT05494749` - Zirconia Reinforced Glass Ionomer in MIH	N/A
Completed	`NCT05931822` - Silver Diamine Fluoride Modified Restoration In Treating Hypomineralized First Permanent Molar.	N/A
Not yet recruiting	`NCT04475419` - Restoration Quality in Molars Affected by Molar Incisor Hypo Mineralization	N/A
Completed	`NCT04061096` - Local Anesthesia in Molar Teeth With Molar Incisor Hypomineralization	N/A
Recruiting	`NCT05748067` - Minimally Invasive Treatment for Permanent Molars Affected With Molar-incisor Hypomineralization Defects	N/A
Not yet recruiting	`NCT03583671` - Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children From 8 to 12 Years Old in Dakahlia
Active, not recruiting	`NCT03870958` - Glass Ionomer Cement Sealant in the Prevention of Post-eruptive Fractures in Molars Affected by MIH	N/A
Completed	`NCT05727475` - Change in OHRQOL Following Minimally Invasive Treatment of Anterior Teeth in Children With MIH	N/A
Completed	`NCT04685889` - Resin Infiltration Treatment for MIH	N/A
Not yet recruiting	`NCT06330272` - Accuracy of Spectrophotometry in Hypomineralized Lesions Treated With CPP-ACPF Dental Mousse: Clinical Study	N/A
Enrolling by invitation	`NCT03233464` - Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Giza Governorate	N/A
Completed	`NCT04103710` - Prevalence of Molar Incisor Hypomineralization Among Children Treated With Asthmatic Drugs Early in Their Lives

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Association Between Molar-Incisor Hypomineralization, Maternal Stress and Anxiety: A Cross-Sectional Study.

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms