Clinical Trials Logo

Mitral Regurgitation clinical trials

View clinical trials related to Mitral Regurgitation.

Filter by:
  • Recruiting  
  • Page 1 ·  Next »

NCT ID: NCT06343363 Recruiting - Heart Failure Clinical Trials

Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety

EARLY-Edge
Start date: May 1, 2023
Phase:
Study type: Observational

Mitral regurgitation (MR) and tricuspid regurgitation (TR) are common causes of breathlessness, fluid retention and other heart failure symptoms, which lead to reduced quality of life and frequent hospitalisation. These conditions are particularly prevalent in older adults with many of these patients being at high risk for surgical intervention due to frailty and comorbidities, leaving them with few treatment alternatives. Transcatheter edge-to-edge repair (TEER) procedures have increasingly been used to improve the severity of both MR and TR, offering patients symptomatic relief and reductions in heart failure hospitalisation at low procedural risk. There is considerable geographic variation in protocols to assess these patients prior to the procedure and also in length of hospital stay. The standard of care in the UK, and particularly in Oxford, emphasises fewer investigations before the TEER procedure and shorter length of hospital stay. This prospective, observational cohort study will examine the safety and feasibility of this practice.

NCT ID: NCT06278727 Recruiting - Heart Failure Clinical Trials

Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy

Start date: January 1, 2024
Phase:
Study type: Observational

This observational study is to develop and validate the prediction model for functional mitral regurgitation regression in heart failure patients taking GDMT. The patients diagnosed ≥2+ functional mitral regurgitation by ultrasonic cardiogram are enrolled in this study and would be clinically followed by at least one year (clinical visit at 3 months, 6 months, and 12 months), and then by when the endpoints are reached.

NCT ID: NCT06266858 Recruiting - Clinical trials for Mitral Regurgitation

Multimodality Imaging Assessment of the Severity of Mitral Regurgitation

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

To investigate to assess the severity of mitral regurgitation by multimodality imaging.

NCT ID: NCT06255457 Recruiting - Clinical trials for Ventricular Tachycardia

Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery

Mitra-VT
Start date: February 21, 2024
Phase:
Study type: Observational

Study objectives: - To assess the impact of mitral valve surgery for mitral regurgitation on ventricular arrhythmic burden and surrogate markers of fibrosis in patients with arrhytmogenic mitral valve prolapse (MVP) from baseline to 6 months after surgery - To characterize the molecular landscape of arrhytmogenic MVP Study design: -Prospective explorative observational study Study population: -90 patients with arrhytmogenic MVP and without arrhytmogenic MVP (controls) eligible for mitral valve surgery for mitral regurgitation will be enrolled. All patients will be evaluated with cardiac magnetic resonance (CMR) imaging and continuous seven day arrhythmic monitoring before and at 6 months after mitral valve surgery

NCT ID: NCT06162780 Recruiting - Clinical trials for Mitral Regurgitation

TEER for Severe DMR of Low to Intermediate Surgery Risk

Start date: January 1, 2024
Phase:
Study type: Observational [Patient Registry]

To investigate the efficacy and safety of transcatheter mitral valve edge-to-edge repair (TEER) for severe degenerative mitral regurgitation (DMR) patients of low to intermediate surgery risk.

NCT ID: NCT06152315 Recruiting - Clinical trials for Mitral Regurgitation

Mitral Splay Sign, Its Mechanism and Association With Severity of Regurgitation

Start date: January 1, 2023
Phase:
Study type: Observational

To study echocardiography splay sign in mitral regurgitation and its association with mitral regurgitation severity and doppler band artifact ('seagull cry').

NCT ID: NCT05925335 Recruiting - Heart Failure Clinical Trials

The China Mviv Registry

Start date: July 11, 2023
Phase: N/A
Study type: Interventional

Mitral valve disease is the most common structure heart disease, and surgical valve replacement is an important treatment for severe mitral valve disease. There are 2 types of valve often been used, mechanical or biological protheses valves. Mechanical valve requires lifelong use of anticoagulants and take the risk of bleeding through all lifetime, but bioprotheses valve do not..

NCT ID: NCT05736289 Recruiting - Clinical trials for Mitral Regurgitation

Evaluation of Mitral Valve Insufficiency Under General Anesthesia

MITIGATE
Start date: February 13, 2023
Phase:
Study type: Observational

Observational study in adult humans undergoing surgical or cardiological intervention for mitral valve insufficiency. Investigators aim to evaluate hemodynamic changes on an arterial pressure waveform level in patients before and after mitral valve intervention using Nexfin (BMEYE, Amsterdam, the Netherlands) continuous non-invasive hemodynamic monitoring, using finger cuff based technology to register beat-to-beat data

NCT ID: NCT05678868 Recruiting - Clinical trials for Mitral Regurgitation

Structural Mitral Valve Project

Start date: February 1, 2022
Phase:
Study type: Observational

This is a prospective Quality Improvement (QI) study using the Model for Improvement framework. The objective of this study is to implement a structured, comprehensive, innovative, and sustainable approach to the management of patients with advanced mitral valve (MV) disease and heart failure (HF) in Southeastern Ontario and to improve healthcare delivery, patient care, and patient outcomes in the context of structural surgical and percutaneous MV interventions. This will be achieved through the strategic implementation, promotion, and evaluation of: i.The first local Southeastern Ontario Structural Mitral Valve Clinic using an Interdisciplinary heart team (IHT) at the Kingston Health Sciences Centre (KHSC) and its integration with the KHSC's existing Heart Failure Clinic; ii.The first provincial Structural Mitral Valve Clinic electronic referral service on the Ontario electronic services platform; and iii.The promotion of the above through targeted KT (Knowledge Transfer) outreach activities. Patients for this study will be recruited through medical referral within the south eastern Ontario, Canada region.

NCT ID: NCT05655897 Recruiting - Clinical trials for Mitral Regurgitation

Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation

Start date: November 24, 2022
Phase: N/A
Study type: Interventional

To observe and evaluate the safety and efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation through a prospective, multicenter clinical trial using objective performance criteria.