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Mite Allergy clinical trials

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NCT ID: NCT05525650 Enrolling by invitation - Rhinitis, Allergic Clinical Trials

Comparative Evaluation of Safety and Immune Activity of New Immunotherapeutic Agents for HDM Allergic Rhinitis Patients

Start date: January 20, 2022
Phase: Phase 1
Study type: Interventional

When administering clinical trial drugs to patients with house dust mite allergic rhinitis, safety/tolerance is comparatively evaluated as the primary outcome, and symptom improvement and immune activity of the disease are comparatively evaluated as secondary outcome.

NCT ID: NCT04915352 Suspended - Respiratory Disease Clinical Trials

Interest of Nasal Provocation Tests for Diagnosis of House Mites Allergic Rhinitis

NPT-MAR
Start date: March 7, 2022
Phase: Phase 4
Study type: Interventional

The aim of this clinical trial is to compare the positive predictive value of the combination rapid nasal provocation test (RNTP) + skin tests (TC) + specific immunoglobulins E (IgEs) to the combination of TC + IgEs (strategy currently used in clinical practice) concerning the efficacy of treatment with Allergen immunotherapy (ITA) at 1 year, in patients with symptoms suggesting allergic rhinitis to house dust mites.

NCT ID: NCT01479205 Completed - Allergic Asthma Clinical Trials

Induction of Allergen Specific Bronchial Immunotolerance After Specific Immunotherapy

ITASIT
Start date: July 2010
Phase: N/A
Study type: Observational

One aim of this study was to find out if the bronchial allergen provocation (BAP) is an appropriate method to appraise the efficacy of a specific immunotherapy (SIT). The investigators had one group of children receiving SIT and one group of patients who denied a SIT although they had an indication for it. Retrospectively the investigators analysed the data of the first BAP and blood parameters specific IgE-mite, total IgE before SIT (November 2008 till February 2010). Prospectively The investigators analysed the lung parameters and allergic labor parameters that we got in the course of the second BAP. The investigators mean parameter was PD20FEV1-mite. Another aim of The investigators study was to find specific immunological differences between children who improved because of SIT and those who showed no improvement. Thus, The investigators compared the levels of total IgE, cumulative IgE-mite and specific IgE-mite before and after SIT and the levels of specific IgG-mite and specific IgG4-mite after SIT.