Clinical Trial Details
— Status: Not yet recruiting
Administrative data
| NCT number |
NCT06448858 |
| Other study ID # |
Minerals in Adolescent |
| Secondary ID |
|
| Status |
Not yet recruiting |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
June 2024 |
| Est. completion date |
June 2025 |
Study information
| Verified date |
June 2024 |
| Source |
Assiut University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational [Patient Registry]
|
Clinical Trial Summary
Evaluation of the concentration of serum Mn, Se, iron, Cu & Zn levels in obese and overweight
adolescents, Correlate the body composition parameters with these minerals' concentration,
Study the association between the metabolic risk factors and the disturbance in minerals
levels in these patients.
Description:
Obesity in the population tends to be a notable public health threat on the global scale .
individuals with higher body mass index (BMI) are considered to have a lower life expectancy
. Among the obesity-related indicators, visceral adipose tissue (VAT) is acknowledged an
emerging and sensitive predictor for the risk of metabolic syndrome and cardiovascular
disease . Therefore, adverse VAT accumulation can influence metabolic health in the
population, and its related risk factors should be further investigated.
Micronutrients in obese people are explored because of an excess energy consumption, and
therefore, an inadequate intake of trace elements and minerals. This imbalance among energy
consumption and the intake is known as hidden hunger. Obesity can lead to nutritional
metabolic disorders, in which the general state of trace elements and minerals are altered.
Only a few studies on child and adolescents obesity concerned Trace Elements (TE). TE is
involved in the pathogenesis of obesity and obesity related diseases. We tried to assess
trace elements status [ Manganese (Mn), selenium (Se) copper (Cu),zinc (Zn)] in obese
children and their relationships with VAT and metabolic risk factors of obesity.
Manganese (Mn) is an essential trace element . It plays an important role in fat metabolism.
Selenium (Se) is an essential micronutrient that acts as an antioxidant and possesses
multiple metabolic properties.
Copper (Cu) is a trace element that is vital. Cu has been reported to play a role in fat
metabolism.
Zinc (Zn) plays an important role. Its deficiency impairs growth, metabolism and immunity.
Iron (Fe) is an essential trace element to sustain all forms of life. Existing research
indicates iron deficiency is one of the comorbidities associated with obesity .
