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Clinical Trial Summary

Recent studies have described the role of melatonin as a sleep regulator and as an anti- oxidative neuroprotective agent in improving sleep quality and delaying cognitive decline in Alzheimer's disease (AD).

In accordance with this data, our hypothesis is that melatonin will delay the cognitive decline in Mild Cognitive Impairment (MCI) patients and reduce the conversion rate from MCI to AD.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00544791
Study type Interventional
Source Assaf-Harofeh Medical Center
Contact Michael khaigrekht, MD
Phone 972-8-9779823
Email khaigrekhtm@asaf.health.gov.il
Status Recruiting
Phase Phase 2
Start date October 2007
Completion date October 2010

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