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Migraine clinical trials

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NCT ID: NCT06221267 Recruiting - Migraine Clinical Trials

A Registry Study on Rimegepant for the Treatment of Migraine Participants in Guangdong-Hong Kong-Macao Greater Bay Area

Start date: January 26, 2024
Phase:
Study type: Observational [Patient Registry]

This study is a single-arm, prospective, multicenter, observational registry study. It plans to enroll 120 migraine patients who meet the inclusion criteria and are treated with rimegepant in selected hospital outpatient clinics in the Greater Bay Area. The main purpose of this study is to observe the effectiveness of rimegepant in treating migraines in a real-world clinical setting, including the impact of rimegepant on the quality of life, functioning, productivity status of migraine patients, and patients' satisfaction with the use of rimegepant in treating migraines.

NCT ID: NCT06212869 Recruiting - Migraine Clinical Trials

Green Light and Transcranial Direct Current Stimulation in Migraine Patients

Start date: January 18, 2024
Phase: N/A
Study type: Interventional

There is a lack of evidence on the clinical outcome of green light exposure, as it is the emerging, novel proposal of treatment. There are a lot of researches present with small sample size which should be done on large population. In last conducted studies, session numbers of the applied modality are less. There is no comparison of tDCS with green light for migraine. The literature suggested the neuromodulation influenced by these interventions that may result in reduction of migraine.

NCT ID: NCT06203678 Recruiting - Migraine Clinical Trials

The Effectiveness of Cervical Kinesio Taping in Migraine

Start date: January 2, 2024
Phase: N/A
Study type: Interventional

Migraine is a common episodic headache disorder accompanied by neurological, gastrointestinal and autonomic changes.Migraine symptoms have a wide range, neck pain is seen in most migraine attacks, and accompanying neck pain is considered one of the important factors that increase migraine-related disability. It has been shown that various physical therapy methods applied to migraine patients with cervical myofascial pain reduce migraine pain and analgesic needs. One of the methods used in myofascial pain syndrome is kinesio taping and the effectiveness of cervical area applications has been shown in different studies.In this study, it was planned to examine the effect of kinesio taping applied to cervical trigger points on migraine symptoms in migraine patients.

NCT ID: NCT06200480 Recruiting - Migraine Clinical Trials

Nurse Intervention Trial

Start date: April 21, 2023
Phase: N/A
Study type: Interventional

This randomized open-label prospective study focus on headache patients initiating preventive treatment, where the treating physician identifies a need for follow-up visits in specialized healthcare. The study will clarify whether the implementation (compliance) and overall satisfaction of the patient are better with follow-up by a headache nurse compared to standard follow-up. Patients with signed written consent will be randomised to either group a: Telephone calls from nurse after two and 6 week or B. Patient-initiated follow-up by their general practitioner.

NCT ID: NCT06191016 Recruiting - Migraine Clinical Trials

Vagal Nerve Stimulation and Pain Frequency, Intensity in Chronic Migraine

Start date: December 26, 2023
Phase: N/A
Study type: Interventional

This study is being conducted to address the need for effective and well-tolerated interventions in preventing chronic migraine attacks. Chronic migraines significantly impact the quality of life for individuals suffering from them, often leading to substantial discomfort and impairment. By evaluating the feasibility, safety, and acceptance of noninvasive vagus nerve stimulation (nVNS), researchers aim to determine if this approach can offer a viable solution for alleviating the frequency and severity of chronic migraine episodes. If successful, this study could potentially introduce a promising new treatment option that enhances the well-being and daily functioning of those affected by chronic migraines.

NCT ID: NCT06182098 Recruiting - Migraine Clinical Trials

Intravenous Fluids in Pediatric Migraine

Start date: June 27, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare intravenous (IV) fluids in pediatric patients with migraine. The main questions it aims to answer are: - Does a large amount of fluids (bolus) improve pain - Does a large amount of fluids (bolus) reduce admissions to the hospital for migraine Participants will be asked to report their pain and have vital signs checked every 30 minutes for two hours. Researchers will compare a large amount of fluids (bolus) to a small amount (half maintenance) to see if there is a difference in pain improvement.

NCT ID: NCT06173661 Recruiting - Migraine Clinical Trials

Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45

Start date: March 1, 2024
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to learn about how a migraine prevention medicine works for people who have migraines/headaches with their menstrual period. The study includes people ages 18 to 45 who have been diagnosed with migraine and who have a migraine with their menstrual period or those who have migraines with their menstrual period and at other times of the month as well. The main question the study aims to answer are: • Does fremanazemab, an injectable calcitonin gene-related peptide (CGRP) pathway targeting therapy, decrease migraines associated with menstruation? Participants will - have an evaluation and examination by a headache specialist physician - will receive the study medicine or inactive substitute every three months for two treatments - fill out diaries about their migraines - have tests on saliva to measure hormone levels Researchers will compare the people who get the medicine to those who get the inactive substitute to see if there are differences in response.

NCT ID: NCT06170411 Recruiting - Migraine Clinical Trials

Post-marketing Clinical Trial of Elexir(Trigeminal Nerve Electrical Stimulator) for the Acute Treatment of Migraine

Start date: October 27, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of treating migraine in the acute phase by applying the acute mode (program 1) of Elexir (trigeminal nerve electrical stimulator) to patients with migraine.

NCT ID: NCT06170281 Recruiting - Migraine Clinical Trials

Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial

SMARTMig
Start date: December 15, 2023
Phase: N/A
Study type: Interventional

This study will unpack the behavioral intervention for migraine and determine the optimum combinations. In addition, the study will test preference and self-selection effects during the trial.

NCT ID: NCT06158737 Recruiting - Migraine Clinical Trials

A Clinical Trial Evaluated the Safety and Tolerability, Pharmacokinetic and Pharmacodynamics Profile, and Immunogenicity of a Single Dose of JS010 Injection in Healthy Subjects

Start date: May 9, 2023
Phase: Phase 1
Study type: Interventional

This study adopts a dose escalation design with six preset dose levels, namely 3mg, 30mg, 150mg, 300mg,600mg, 900mg, single subcutaneous injection. A total of 48 healthy subjects will be enrolled in the experiment, 8 in each group.They will be randomly assigned to receive JS010 injection and matching placebo in a ratio of 3:1. In accordance with the dose-escalation principle,Starting from the lowest initial dose, increasing to the higher dose and proceeding in sequence. Each subject can receive only one dose Level of single subcutaneous administration.