Migraine With Aura Clinical Trial
Official title:
Migraine and Endothelial Dysfunction
Recently, there is evidence that endothelial activation and dysfunction are associated with migraine, especially in female migraineurs with aura. Our objectives were to determine whether novel endothelial function markers are altered in female migraineurs with aura compared to age-matched controls.
Our objectives were to determine whether novel endothelial function methods and novel markers
of endothelial activation are associated with migraine in female migraineurs with aura.
Migraine is an independent risk factor for stroke, especially in young women with aura
symptoms. Endothelial dysfunction is a risk factor for cardiovascular diseases. Recent
studies suggest that there is a link between migraine with aura and endothelial activation,
dysfunction and impaired vascular reactivity.
In this case-control study the investigators examine several novel biomarkers of endothelial
function such as endothelial progenitor cells and endothelial microparticles as well as novel
methods such as reactive hyperemic peripheral arterial tonometry in female migraineurs with
aura and age-matched controls.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02253004 -
Induction of Migraine Aura With Cilostazol
|
Phase 0 | |
| Recruiting |
NCT02202486 -
Investigation of the Blood-brain and Blood-dura Barrier Durin Migraine Attacks Using MRI
|
N/A | |
| Completed |
NCT00123201 -
Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment of Migraine Headache
|
Phase 2 | |
| Completed |
NCT04406649 -
A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migraine
|
Phase 3 | |
| Completed |
NCT03874832 -
A Phase I Study to Study the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects
|
Phase 1 | |
| Recruiting |
NCT05565001 -
The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain.
|
N/A | |
| Recruiting |
NCT05416476 -
Anisodine Hydrobromide For The Preventive Treatment Of Episodic Migraine
|
Phase 3 | |
| Active, not recruiting |
NCT02906085 -
Endothelin-1 as a Potential Trigger of Migraine Aura
|
N/A | |
| Recruiting |
NCT00893594 -
Efficacy of Sumatriptan With Naprosyn in Migraine With Aura
|
N/A | |
| Completed |
NCT00534560 -
Dose Ranging Study of the Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache
|
Phase 2 | |
| Terminated |
NCT04936061 -
Transnasal Cooling for Migraine
|
N/A | |
| Recruiting |
NCT05281770 -
Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study
|
||
| Not yet recruiting |
NCT04063540 -
Acid-Sensing Ion Channel and Migraine Disease Proof of Concept Study on the Efficacy of Amiloride in the Prophylaxis of Migraine Aura
|
Phase 2 | |
| Completed |
NCT03472417 -
Partial Rebreathing in the Treatment of Migraine With Aura
|
N/A | |
| Completed |
NCT00334178 -
Evaluation of the Efficacy and Safety of Laxymig® as Prophylactic Treatment in Patients With Migraine
|
Phase 3 | |
| Recruiting |
NCT06051604 -
Mi-Helper Transnasal Cooling for Acute Treatment of Migraine
|
N/A | |
| Recruiting |
NCT06414044 -
Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients
|
||
| Completed |
NCT03472378 -
Can DFN-15 Terminate Migraine With Allodynia?
|
Phase 2 | |
| Recruiting |
NCT05211154 -
Evaluation of the Efficacy of Diclofenac Potassium and Rimegepant for the Acute Treatment of Migraine
|
Phase 4 | |
| Completed |
NCT02708797 -
Brainstem Grey Matter and Cerebral Autoregulation in Migraine With Aura.
|
N/A |