Efficacy of Pregabalin in Migraine Prevention

Status Withdrawn

Clinical Trial Summary

The purpose of this study is to evaluate the efficacy and safety of pregabalin in comparison with sodium valproate in migraine prevention with a randomized blinded crossover study.

Clinical Trial Description

The anticonvulsants are effective in the treatment of migraine prevention. The sodium valproate has demonstrated to be effective as monotherapy for migraine prevention in placebo-controlled trials. Besides, other new drugs like gabapentin have been used in the prevention of migraine with a good level of evidence. The pregabalin is an anticonvulsant that has not been proved to use in migraine prevention and it has a similar action mechanisms of the gabapentin. The purpose of this study is the comparison of the effect of pregabalin and sodium valproate in migraine prevention in a randomized blinded crossover study. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Migraine Disorders

Clinical Trial Details

NCT number	NCT00447369
Study type	Interventional
Source	Hospital Militar del General Luis Felipe Brieba Aran
Contact
Status	Withdrawn
Phase	Phase 3
Start date	May 2007
Completion date	March 2008

View Details

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