Impact of Quinoa Milk Fermented With Lactic Acid Bacteria From Foods on Human Oral and Intestinal Flora

Microbial Colonization Clinical Trial

Official title:

Impact of Quinoa Milk Fermented With Lactic Acid Bacteria From Foods on Human Oral and Intestinal Flora

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04280731
• Other study ID #: FermCH
• Status: Completed
• Phase: N/A
• Start date: January 7, 2020
• Est. completion date: June 20, 2020

Study information

• Verified date: October 2020
• Source: Lund University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The demand for alternatives to dairy products has increased in recent years and a lot of proposals for vegetable milk and yogurt products have taken place in the market. Quinoa is a plant from South America that has growth in popularity in recent years as many sought out nutritious and healthier eating, the herb is known for its high nutritional value. It is complete protein source containing all the essential amino acids. If this herb were fermented with probiotic bacteria, there is a potential for a product that is lactose free, gluten free and cholesterol free.

The probiotic potential of quinoa milk, fermented with food associated lactic acid bacteria will be investigated. This includes a study that examines how daily consumption of this vegetable drink changes the composition of the oral and intestinal flora. Therefore, healthy people are now seeking to participate in the study, which will be for just over 2 weeks.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: June 20, 2020
• Est. primary completion date: June 20, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Above 18 years and healthy volunteers

Exclusion Criteria:

• Participants that have any kind of diseases, such as colon inflammation

Related Conditions & MeSH terms

• Communicable Diseases
• Infection
• Microbial Colonization

Intervention

Dietary Supplement:
• fermented quinoa
Quinoa drink fermented with lactic acid bacteria isolated from food

Locations

Country	Name	City	State
Sweden	Kemicentrum	Lund	Skåne

Sponsors (2)

Lead Sponsor	Collaborator
Lund University	Swedish International Development Cooperation Agency (SIDA)

Country where clinical trial is conducted

Sweden, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Survivability of the lactic acid bacteria	If the bacteria can be isolated in a adequate amount by cultivation on MRS broth and rogosa agar	2 weeks
Secondary	Changes in the human microbiota	Changes in the saliva and stool samples by analyzes with Terminal Restriction Fragment Length polymorphism	2 weeks
Secondary	Changes in the human microbiota	Changes in the saliva and stool samples by quantitative polymorphic chain reaction	2 weeks