Metastatic Pancreatic Cancer Clinical Trial
Official title:
BrUOG-PA-205 A Phase I Trial of GW572016, Gemcitabine and Oxaliplatin for Metastatic Pancreaticobiliary Cancer Schema GSK Study ProtocolGSK #103556
A Phase I Trial of GW572016, Gemcitabine and Oxaliplatin for Metastatic Pancreaticobiliary Cancer Schema
The primary objective of this phase I study is to determine the safety, tolerability and
optimal tolerated regimen of GW572016 when combined with gemcitabine and with the combination
of gemcitabine and oxaliplatin. Three to six patients will be treated at each dose level to
assess toxicity. To better assess the safety at the final dose level in both Stage I and
Stage II, the number of patients in the cohort at the Maximum Tolerated Dose for both Stages
will be expanded to 10. Therefore approximately 34-37 patients will be treated on this study.
Trial finished and no further data will be collected.
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