Metabolic Syndrome Clinical Trial
Official title:
Non-invasive Measurement of Energy Metabolism in Patients With Primary and Secondary Mitochondrial Diseases
Energy metabolism and insulin sensitivity were assessed in a case-control study in patients with branched-chain organic acidemias.
Children and adults with branched-chain organic acidemias and matched healthy humans underwent deep metabolic phenotyping using non-invasive magnetic resonance spectroscopy, oral glucose tolerance tests and measurements of leucocyte respirometry in order to assess changes in energy metabolism and insulin sensitivity. ;
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