Resistance and/or Endurance Training, What is Most Effective in Prevention of Cardiovascular Diseases?

Metabolic Syndrome Clinical Trial

Official title:

Strength Training Versus Aerobic Interval Training to Modify Risk Factors of the Metabolic Syndrome

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00986024
• Other study ID #: 460150
• Status: Completed
• Phase: N/A
• First received: September 28, 2009
• Last updated: December 12, 2012
• Start date: August 2006
• Est. completion date: March 2007

Study information

• Verified date: December 2012
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway:National Committee for Medical and Health Research Ethics
• Study type: Interventional

Clinical Trial Summary

The aim of the present study was to evaluate the effects of aerobic interval training versus strength training or a combination of these regimes on factors comprising the metabolic syndrome in order to find the most effective exercise regime for patients with metabolic syndrome.

Description:

In the Western world, approximately 25% of young to middle-aged adults have metabolic syndrome. There seem to be a strong age-dependence in the prevalence of the metabolic syndrome, but the incidence rises rapidly within adolescents and middle-aged groups and follows the development of obesity in the general population. Metabolic syndrome confers an increased risk of coronary heart disease, cardiovascular disease, and premature death; therefore, effective and affordable strategies to combat the syndrome would be of great individual and social importance.

Despite the general agreement that moderate-intensity physical activity for a minimum of 30 min five days per week or vigorous-intensity aerobic physical activity for a minimum of 20 min three days a week promote and maintain health, the optimal training regime to treat metabolic syndrome and its associated cardiovascular abnormalities remains uncertain.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 31
• Est. completion date: March 2007
• Est. primary completion date: March 2007
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 20 Years to 70 Years

Eligibility

Inclusion Criteria:

• Having metabolic syndrome according to international diabetes foundations definition (IDF).

Exclusion Criteria:

• Unstable angina pectoris

• Uncompensated heart failure

• Myocardial infarction during the past 4 weeks

• Complex ventricular arrhythmias

• Kidney failure

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Metabolic Syndrome
• Metabolic Syndrome X

Intervention

Behavioral:
• aerobic exercise
carried out 3 times per week for 12 weeks
• strength training
carried out 3 times per week for 12 weeks

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology

References & Publications (1)

Stensvold D, Slørdahl SA, Wisløff U. Effect of exercise training on inflammation status among people with metabolic syndrome. Metab Syndr Relat Disord. 2012 Aug;10(4):267-72. doi: 10.1089/met.2011.0140. Epub 2012 Mar 28. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	proinflammatory markers	circulating interleukin-18 and interleukin-6	12 weeks	No