Estrogen Diastolic Heart Failure

Status Terminated

Clinical Trial Summary

Peri-menopausal women will be randomized to hormone replacement therapy or placebo for 12 weeks to determine if markers of systolic and diastolic function change by echocardiography as well as laboratory markers of heart failure, including b-type natriuretic peptide (BNP).

Clinical Trial Description

This preliminary, feasibility study will randomize 28 peri-menopausal women to either hormone replacement therapy or placebo for 12 weeks. Prior to randomization, each participant will undergo echocardiography, measurements of activity using the Duke Activity Status Index, measurements of quality of life and laboratory data, including b-type natriuretic peptide (BNP) measurements. Following the intervention for 12 weeks, these measurements will all be repeated. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02693002
Study type	Interventional
Source	University of Kentucky
Contact
Status	Terminated
Phase	Phase 4
Start date	February 2016
Completion date	November 2016

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