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Menopause clinical trials

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NCT ID: NCT02618148 Completed - Menopause Clinical Trials

Hormone Estradiol Replacement Therapy Additional Herbals

WH
Start date: January 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether Hormone Replacement Therapy (HRT), safety studies are combined with herbal (garlic oil, rutin, and nattokinase) to reduce estrogen side effects. Making it safer when an endocrine supplement is needed for estrogen deficiency symptoms in menopausal and postmenopausal women.

NCT ID: NCT02587676 Completed - Menopause Clinical Trials

Deterioration of Resilient Denture Liners and Patient Characteristics

Start date: June 2013
Phase: N/A
Study type: Observational

Thirty complete maxillary denture wearers were recruited after obtaining informed consent. One investigator measured the Shore D hardness of the commercially available RDLs using a Vesmeter®. The salivary flow rates and pH values and the occlusal force were measured for all patients before initiation of the study. T-tests and Pearson's correlation coefficients were used for statistical analyses. A p-value of <0.05 was considered statistically significant.

NCT ID: NCT02534064 Completed - Clinical trials for Vitamin D Deficiency

Effect of Consumption of Yogurt Fortified in Calcium and Vit. D on Circulating Levels of 25OHD in Postmenopausal Women

Start date: October 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of daily consumption of one or two CALIN+ pot(s) versus no intake of product, after 4, 8, 12 and 16 weeks, on the evolution of the serum concentration of 25-hydroxy vitamin D (25OHD) (D2 + D3) in postmenopausal women.

NCT ID: NCT02516202 Completed - Menopause Clinical Trials

The Vaginal Health Trial

Start date: April 2016
Phase: Phase 3
Study type: Interventional

This is a new application from the Menopause Strategies: Finding Lasting Answers for Symptoms and Health (MsFLASH) Clinical Trials network. Here we propose to conduct a large multicenter trial comparing two common treatments, a vaginal hormone tablet and an over-the-counter gel, with placebo to evaluate their effects on bothersome vaginal symptoms and sexual function, and to create a biorepository of specimens for future translational, mechanistic research on the etiology of vaginal symptoms.

NCT ID: NCT02497560 Terminated - Menopause Clinical Trials

A Study To Investigate The Effect Of A Natural Dietary Supplement On Peri-Menopausal Symptoms

Start date: March 2015
Phase: Phase 2/Phase 3
Study type: Interventional

This is a randomized, masked, placebo controlled study to assess the effect on a nutritional dietary supplement on menopausal signs and symptoms in perimenopausal women.

NCT ID: NCT02496338 Completed - Menopause Clinical Trials

Menopausal Health Training for Husbands on Women's Quality of Life and Marital Satisfaction

Start date: May 2014
Phase: N/A
Study type: Interventional

The investigators conducted a clinical trial to evaluation the effect of a menopausal health training for Husbands of 45-60 years women on the women's quality of life and marital satisfaction during transitional period to menopause.

NCT ID: NCT02471755 Completed - Menopause Clinical Trials

Electro-acupuncture for Menopausal Transition Symptoms

Start date: April 2013
Phase: N/A
Study type: Interventional

This trial aimed at exploring the efficacy as well as safety of electro-acupuncture for MT symptoms.

NCT ID: NCT02460302 Withdrawn - Menopause Clinical Trials

Vaginal Progesterone Versus Placebo for the Treatment of Vaginal Atrophy

Start date: December 2016
Phase: Phase 2
Study type: Interventional

Atrophic vaginitis affects the majority of post-menopausal women. It is characterized by dryness and inflammation of the vagina, with thinning of the vaginal tissues. Atrophic vaginitis is caused by the decreased effect of estrogens post menopause. Traditionally, local estrogens have been used to treat atrophic vaginitis Studies have shown that there are progesterone receptors in vaginal tissues. The use of progesterone to treat atrophic vaginitis has not yet been studied. However, its use has been studied in other populations including as a fertility medication in pregnant women. There is a significant group of women who cannot use, choose not to use, or do not respond to estrogenic therapies. The goal of this study is to evaluate the efficacy of vaginal progesterone in the treatment of urogenital atrophy, compared to placebo. This study is a randomized, double-blind, placebo controlled trial. The ultimate goal is to expand the treatment options for patients with symptoms of vaginal atrophy.

NCT ID: NCT02449902 Completed - Menopause Clinical Trials

TXV13-01 Estradiol Vaginal Softgel Capsules in Treating Postmenopausal Women With Symptoms of Vulvar and Vaginal Atrophy

Start date: July 2013
Phase: Phase 2
Study type: Interventional

The study was designed to evaluate the efficacy and safety of TX-12-004-HR 10 μg in treating moderate to severe symptoms of vaginal atrophy associated with menopause after 14 days of treatment, and to estimate the effect size and variability of vulvovaginal atrophy endpoints. In addition, the systemic exposure to estradiol from single and multiple doses of TX-12-004-HR was to be investigated.

NCT ID: NCT02445716 Recruiting - Menopause Clinical Trials

Transdermal Testosterone Nanoemulsion in Women Libido

Biolipid/B2
Start date: October 2015
Phase: Phase 2
Study type: Interventional

This is a double-blind, randomized, placebo-controlled study. Seventy women, aged 35-75 years, with treatment-emergent loss of libido will be randomly allocated to the treatment with a Transdermal nanoemulsion of Testosterone (500mcg) delivering 300 mcg of testosterone/day or an identical placebo nanoemulsion (PLA) for 12 weeks.