Clinical Trials Logo
  1. Home
  2. Meniscus Lesion
  3. NCT03066583

Effectiveness of Trephination With Platelet Rich Plasma or Placebo in a Primary Meniscal Tear Treatment — Prolotherapy  

Meniscus Lesion Clinical Trial

Official title:
Prospective, Randomised, Double Blinded Trial Comparing Effectiveness of Platelet Rich Plasma or Placebo in a Primary Meniscal Tear Treatment

Clinical Trial Summary

This study will compare meniscal healing augmented or without augmentation with platelet rich plasma in primary meniscal tear treatment (prolotherapy). The assessments will include validated, disease specific, patient oriented outcome measures. Results of this study will help ascertain whether platelet rich plasma may improve meniscal healing rates.

Clinical Trial Description

The role of meniscal in the knee integrity is pivotal and lack or partial role of the meniscus increases rate of joint degeneration. Partial meniscal removal is the most popular procedure and meniscal repair remain in minority of arthroscopic surgeries. As criteria of inclusion to meniscal repair are very rough, still success rates of meniscal repair remain in the 60-80% range for isolated repairs. This rate is greater when performed with ACL reconstruction. The investigators believe that augmentation with platelet rich plasma as prolotherapy ill induce healing without the need for arthroscopy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03066583
Study type Interventional
Source Centre of Postgraduate Medical Education
Contact
Status Completed
Phase Phase 2/Phase 3
Start date January 2016
Completion date June 2020
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04228367 - JuggerStitch Post Market Clinical Follow-up Study N/A
Recruiting NCT03479775 - Muscle Function and Traumatic Knee Injury in Sports
Recruiting NCT05882591 - Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment N/A
Recruiting NCT05322005 - Study of Clinical Performance and Safety of Treatments in Degenerative Meniscopathy With Injection of Polynucleotides N/A
Recruiting NCT04436523 - Blood Flow Restriction After Meniscus Repair N/A
Completed NCT05370937 - Clınıcal Results of Evelator and Free Knot Methods In Medial Menıscus Posterior Root Tears N/A
Recruiting NCT06159153 - Dynamic Ultrasonography VS MRI in the Evaluation of Meniscal Lesions in Patients With an Indication for Arthroscopy N/A
Completed NCT01254825 - The Efficacy of Adductor-Canal-Block (ACB) in Patients After Knee Arthroscopy Phase 4
Recruiting NCT04153643 - Meniscus Surgery Registry
Completed NCT03966638 - Clinical and Radiological Evaluation of Meniscal Healing After Percutaneous Intra-meniscal Injection of Platelet-rich Plasma (PRP)
Not yet recruiting NCT03490799 - Muskloskeletal Ultrasound Versus Magnetic Resonance Imaging in Meniscal Abnormalities
Recruiting NCT06376422 - Sterile Allogeneic Spongioflex® Allograft as Partial Meniscal Replacement After Incomplete Meniscal Loss N/A
Recruiting NCT05261360 - Clinical Efficacy of Exosome in Degenerative Meniscal Injury Phase 2
Recruiting NCT04607538 - The Faroese Knee Cohort: Etiology and Long-term Implications of Trochlear Dysplasia and Patellar Dislocations.
Completed NCT05048420 - THE EFFECT OF RAMP LESION REPAIR ON RETURN TO SPORTS IN ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION N/A
Completed NCT04921202 - Metabolic Syndrome and Degenerative Meniscus Lesions Related Knee Function
Recruiting NCT03968029 - Does Wrapping With Bone Marrow Injection Enhance Healing of Meniscal Sutures Into the Avascular Area N/A
Not yet recruiting NCT05505747 - Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair Phase 2/Phase 3
Withdrawn NCT01991353 - Platelet Rich Plasma Study With Meniscal Repair N/A
Completed NCT02322372 - Femoral Blockade and Low-dose Spinal Anesthesia in Outpatient Knee Arthroscopy Phase 4