Meningitis, Meningococcal Clinical Trial
Official title:
A Randomized, Double-Blind, Controlled, Non-inferiority Phase III Trial of a Group A and C Meningococcal Polysaccharide Vaccine in Healthy Children Aged 2-6 Years
This study is a randomized, double-blinded, and controlled phase III clinical trial of the Group A and C meningococcal polysaccharide vaccine to evaluate the safety and immunogenicity of the vaccine in healthy infants aged 2-6 years.
This study was divided into two stages. The first stage study was an early safety assessment study among 80 subjects. The first stage study was conducted gradually in 20 subjects aged 18-50 years, 20 subjects aged 7-17 years, and 40 subjects aged 2-6 years. The second phase was a randomized, double-blind, controlled, non-inferiority phase III clinical trial in 1200 healthy infants aged 2-6 years, to evaluate the immunogenicity and safety of the experimantal vaccine after immunization. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04689165 -
A Phase III Clinical Trial of the Group A Meningococcal Polysaccharide Vaccine
|
Phase 3 | |
| Completed |
NCT00780806 -
Safety And Blood Collection Study Of Meningococcal B Rlp2086 Vaccine In Adults
|
Phase 1/Phase 2 | |
| Completed |
NCT03378258 -
Petechiae In Children (PIC) Study: Defining A Clinical Decision Rule for The Management Of Fever and Non-Blanching Rashes In Children Including The Role Of Point Of Care Testing For Procalcitonin & Neisseria Meningitidis DNA.
|
||
| Completed |
NCT03205371 -
Immunogenicity and Safety of a Meningococcal Conjugate Vaccine Given Concomitantly With Other Vaccines in Toddlers
|
Phase 3 | |
| Completed |
NCT01352793 -
A Global Phase 3 Safety Study of 120 mcg rLP2086 Vaccine in Adolescents and Young Adults Aged 10 to 25 Years
|
Phase 3 | |
| Not yet recruiting |
NCT06113198 -
A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants From 2 Months of Age
|
Phase 4 | |
| Completed |
NCT03295318 -
Clinical Study of Meningococcal ACYWX Conjugate Vaccine, in 12-16 Month Olds
|
Phase 2 | |
| Completed |
NCT03493919 -
A Sourcing Study to Collect Human Blood Samples From Healthy Adults
|
Phase 4 | |
| Completed |
NCT00474526 -
A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Vaccine In Infants
|
Phase 3 | |
| Completed |
NCT00297687 -
Study Evaluating the Safety, Immunogenicity and Tolerability of Meningococcal Group B Vaccine in Healthy Adults
|
Phase 1 | |
| Recruiting |
NCT04665791 -
A Human Controlled Infection Study With Neisseria Lactamica in Malian Adults
|
N/A | |
| Withdrawn |
NCT03431675 -
Ciprofloxacin for the Prevention of Meningococcal Meningitis 2018
|
Phase 4 | |
| Recruiting |
NCT02878291 -
Safety Study of Meningococcal ACYW135 Polysaccharide Conjugate Vaccine in Healthy Volunteers Aged Above 3 Months
|
Phase 1 | |
| Completed |
NCT00314041 -
Study Evaluating the Tolerance of Conjugate Meningococcal C Vaccine in Infants
|
Phase 2 | |
| Recruiting |
NCT04685850 -
Long-term Sequelae of Childhood Meningitis and Meningococcal Purpura Fulminans
|
||
| Completed |
NCT03587207 -
Study to Assess Potential Immune Interference When GlaxoSmithKline (GSK) Biologicals' MenABCWY Vaccine is Administered to Healthy Subjects Aged 10-25 Years
|
Phase 2 | |
| Completed |
NCT03824093 -
High and Low Resource Interventions to Promote HPV Vaccines
|
N/A | |
| Completed |
NCT04707391 -
Immunogenicity and Safety Study of GSK's MenABCWY Vaccine in Healthy Adolescents and Adults Previously Primed With MenACWY Vaccine
|
Phase 3 | |
| Terminated |
NCT00798304 -
Study Evaluating Safety, Tolerability, and Immunogenicity of Meningococcal B Vaccine in Healthy Infants
|
Phase 2 | |
| Recruiting |
NCT03682939 -
Evaluation of Safety and Immunogenicity of Meningococcal B and Meningococcal ACWY Vaccine in at Risk Population
|
Phase 4 |