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Clinical Trial Summary

The purpose of this study is to evaluate the efficacy of lenvatinib and pembrolizumab to treat metastatic uveal melanoma.


Clinical Trial Description

This is a phase II, single arm, single institution clinical trial. Adults (ageā‰„18 years-old) with immune checkpoint inhibitor naïve metastatic uveal melanoma will be evaluated for eligibility. Eligible participants will be treated with the combination of Lenvatinib 20 mg daily + pembrolizumab 200 mg IV every 3 weeks for a maximum of 2 years. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05308901
Study type Interventional
Source Providence Health & Services
Contact Chris Fountain, RN
Phone 503-215-2691
Email christopher.fountain@providence.org
Status Recruiting
Phase Phase 2
Start date August 2, 2022
Completion date June 1, 2026

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Active, not recruiting NCT02874040 - Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser) N/A