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Study of Alterations in Tumor Metabolism Associated With the Development of Immunotherapy Resistance in Melanoma — MEL-META  

Melanoma (Skin) Clinical Trial

Official title:
Study of Alterations in Tumor Metabolism Associated With the Development of Immunotherapy Resistance in Melanoma

Clinical Trial Summary

Among the mechanisms responsible for resistance to immunotherapy, metabolism seems to play a major role. A better understanding of tumor metabolism appears to be absolutely necessary in order to propose efficient therapeutic alternatives to target tumor cells without exerting a deleterious effect on the cells responsible for the anti-tumor immune response. The main objective is to evaluate metabolism modulations in melanoma cells extracted from metastases of patients sensitive and resistant to immunotherapies (anti-PD1 or anti-PD1+anti-CTLA4).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05307289
Study type Interventional
Source Centre Hospitalier Universitaire de Nice
Contact Montaudie Henri
Phone +33492036488
Email montaudie.h@chu-nice.fr
Status Recruiting
Phase N/A
Start date May 25, 2022
Completion date October 25, 2028
View Details
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