Pilot Trial to Evaluate the Effect of Vitamin D on Melanocyte Biomarkers

Melanoma, Skin Clinical Trial

Official title: Pilot Trial to Evaluate the Effect of Vitamin D on Melanocyte Biomarkers

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to determine the signaling pathways and changes in gene expression in melanocytes of subjects with a history of non-melanoma skin cancer who are exposed to oral vitamin D. If vitamin D is found to inhibit a signaling pathway involved in the development of melanoma such as BRAF, a protein involved in cell proliferation, then oral vitamin D could be explored further as a chemoprevention for melanoma skin cancer.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Melanoma, Skin

• NCT number: NCT01477463
• Study type: Interventional
• Source: Stanford University
• Status: Active, not recruiting
• Phase: N/A
• Start date: September 2012
• Completion date: December 2014