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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT05028491
Other study ID # hf-meibomian glands
Secondary ID
Status Completed
Phase
First received
Last updated
Start date October 1, 2020
Est. completion date July 29, 2021

Study information

Verified date August 2021
Source Wenzhou Medical University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

To evaluate the influence of corneal-aberrations before and after the meibomian gland thermal massage treatment.


Description:

62 MGD patients treated with meibomian gland thermal massage once a week for 3 to 4 weeks were recruited.The Ocular Surface Disease Index questionnaire; tear film assessment encompassing tear meniscus height and non-invasive keratograph breakup time ; meibography score,corneal fluorescein staining; the Schirmer I test ; expressible meibomian gland, and quality ,anterior and total corneal aberrations were evaluated before and after treatment.


Recruitment information / eligibility

Status Completed
Enrollment 62
Est. completion date July 29, 2021
Est. primary completion date June 29, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria: - tear break-up time (BUT) =10 seconds or Schirmer I test (SIT) =10 mm, the presence of dry eye symptoms, and fluorescein staining (FL) score <3 points and at least one lid margin abnormality and poor meibomian gland expressibility Exclusion Criteria: - eyelid structure abnormal(Entropion , ectropion); - having received any other treatment for MGD within three months - history of ocular surgery - contact lens use - ocular infection - any type of corneal scarring

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
China Eye Hospital of Wenzhou Medical College Wenzhou Zhejiang

Sponsors (1)

Lead Sponsor Collaborator
Wenzhou Medical University

Country where clinical trial is conducted

China, 

Outcome

Type Measure Description Time frame Safety issue
Primary corneal aberration corneal aberrations Corneal aberrations were measured with a Pentacam? The anterior corneal wavefront aberration was expanded with normalized Zernike polynomials.The corneal aberration from 3rd to 6th order were recorded as the root mean square (RMS) for analysis. baseline and 1 week after treatment
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