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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01942642
Other study ID # 4-2012-0690
Secondary ID
Status Completed
Phase N/A
First received August 29, 2013
Last updated September 13, 2013
Start date November 2012
Est. completion date April 2013

Study information

Verified date September 2013
Source Yonsei University
Contact n/a
Is FDA regulated No
Health authority Korea: Institutional Review Board
Study type Observational

Clinical Trial Summary

Meibomian gland dysfunction (MGD) is a common and important disease has been investigated the pathophysiology, diagnosis, treatment modalities of MGD, however, the changes of MGD after the cataract surgery, the most popular surgery to ophthalmologist, had not been evaluated. The investigators evaluated parameters related with MGD including lid margin abnormalities, meibomian gland expressibility and meibography before and after surgery.


Recruitment information / eligibility

Status Completed
Enrollment 48
Est. completion date April 2013
Est. primary completion date April 2013
Accepts healthy volunteers No
Gender Both
Age group 45 Years to 88 Years
Eligibility Inclusion Criteria:

1. Patients scheduled for cataract surgery

Exclusion Criteria:

1. other comorbid ocular diseases such as ocular allergies.

2. continuous use of topical ocular medications before surgery

3. histories of ocular surgery, or ocular injury

4. Already had severe obstructive MGD before surgery, abnormal findings on lid margin (> 3 positive findings), reduced meibum expression (> grade 2), and obstructed gland dropout (meibography score > 3)

Study Design

Observational Model: Case-Only, Time Perspective: Prospective


Related Conditions & MeSH terms


Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Yonsei University

Outcome

Type Measure Description Time frame Safety issue
Primary Ocular parameters Ocular symptom score, lid margin abnormalities, superficial punctuate keratopathy, tear film break-up time, Shirmer's test, lower tear meniscus height (TMH), depth (TMD), and area (TMA), meibum expressibility, and meibography score change of Ocular parameters from 1 to 3 months after cataract surgery No
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