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Clinical Trial Summary

The reason for this study is to see if the study drug selpercatinib is safe and more effective compared to a standard treatment in participants with rearranged during transfection (RET)-mutant medullary thyroid cancer (MTC) that cannot be removed by surgery or has spread to other parts of the body. Participants who are assigned to the standard treatment and discontinue due to progressive disease have the option to potentially crossover to selpercatinib.


Clinical Trial Description

Adaptive sample size re-estimation will be performed at interim analysis. The sample size could be increased from approximately 250 to 400 depending on the results of interim analysis. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04211337
Study type Interventional
Source Eli Lilly and Company
Contact
Status Active, not recruiting
Phase Phase 3
Start date February 11, 2020
Completion date February 28, 2026

See also
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