Medication Adherence in Patients With Liver Cirrhosis

Medication Adherence Clinical Trial

Official title: Medikamentenadhärenz Bei Patientinnen Und Patienten Mit Leberzirrhose

Status Active, not recruiting

Clinical Trial Summary

With this unfunded, investigator-initiated prospective, observational, explorative, single-arm and diagnostic single-centre study the investigators aim to evaluate medication adherence in patients with advanced liver cirrhosis

Clinical Trial Description

The main objective of the study is to investigate drug adherence in cirrhotic patients and to gain a better understanding of the causes of deficient adherence including evaluation for medication beliefs, satisfaction, depression, anxiety and health-related quality of life. A number of long-term medications have been approved for this group of patients in various indications and / or recommended by guidelines. However, adherence has not been adequately investigated yet. The investigators aim to focus on the following groups of ingredients / classes:

• Primary and secondary antibiotic prophylaxis (e.g. Norfloxacin)

• Non-selective beta-blockers (e.g. Carvedilol and Propranolol)

• diuretics (Spirolactones [e.g. Spironolacton], loop diuretics) Methodically, this is will be investigated in particular by taking into account the patients history, standardized questionnaires and validated interviews. ;

Related Conditions & MeSH terms

• Medication Adherence

• NCT number: NCT03627338
• Study type: Observational
• Source: Hannover Medical School
• Status: Active, not recruiting
• Start date: September 1, 2018
• Completion date: May 31, 2021