Phase I, Dose-escalation Trial of BAY1187982 in Subjects With Advanced

Updated 05/03/2024

Status Terminated

Clinical Trial Summary

To evaluate the safety, tolerability, maximum tolerated dose, pharmacokinetics, and pharmacodynamics of the anti-FGFR2 antibody drug conjugate BAY1187982 in subjects with advanced solid tumors known to express fibroblast growth factor receptor 2 (FGFR2)

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Medical Oncology

Clinical Trial Details

NCT number	NCT02368951
Study type	Interventional
Source	Bayer
Contact
Status	Terminated
Phase	Phase 1
Start date	March 24, 2015
Completion date	July 27, 2016

See also
	Status	Clinical Trial	Phase
	Completed	`NCT02824042` - Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole	Phase 1
	Completed	`NCT02253420` - COPANLISIB (BAY80-6946) Drug-drug Interaction and Cardiovascular Safety Study in Advanced Solid Tumor and Non-Hodgkin's Lymphoma Patients	Phase 1
	Completed	`NCT02357953` - Transpulmonary Thermodilution Using an Implented Central Venous Access Port	N/A
	Completed	`NCT02645357` - Implementing an Evidence-based Computerized Decision Support System Linked to Electronic Health Records to Improve Care for Cancer Patients	N/A
	Recruiting	`NCT04931329` - Onco-haematology Vigilance Card
	Terminated	`NCT02138812` - Phase I Dose Escalation of Oral BAY1161909 in Combination With Intravenous Paclitaxel	Phase 1
	Recruiting	`NCT05356182` - A Pilot and Feasibility Study of a Dietary Intervention With Low-protein Meals in Cancer Patients Receiving Immunotherapies	N/A
	Not yet recruiting	`NCT05423808` - Geriatric and Oncological Evaluation With Technology for Holistic Healthcare Management for Older Multimorbid Patients.	N/A
	Terminated	`NCT02439346` - Phase I Dose Escalation and Expansion of Oral BAY 1143269 in Combination With Intravenous Docetaxel	Phase 1
	Recruiting	`NCT05385718` - Ezra Faster Scan Study
	Completed	`NCT02457351` - Roniciclib (BAY 1000394) Drug-Drug Interaction (DDI) Study	Phase 1
	Completed	`NCT02906423` - Results From a Health System-wide Implementation of a Quality of Life Questionnaire	N/A
	Completed	`NCT01409135` - A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4	Phase 1
	Not yet recruiting	`NCT02327806` - The Effect of Pullsed Magnetic Field Induction on Improving the Forearm Tissue Muscle Performance	N/A
	Completed	`NCT02639091` - Phase Ib Study of Anetumab Ravtansine in Combination With Pemetrexed and Cisplatin in Mesothelin-expressing Solid Tumors	Phase 1
	Completed	`NCT02366949` - Phase I Study of Oral BAY 1217389 in Combination With Intravenous Paclitaxel	Phase 1
	Not yet recruiting	`NCT06097533` - Improvement of Quality of Life by Cannabinoids in Oncologic Patients	Phase 2/Phase 3
	Completed	`NCT02427490` - A Problem-Solving Intervention for Family Caregivers in Palliative Oncology	N/A
	Recruiting	`NCT05359848` - A Pilot, Feasibility Study of Intermittent Caloric Restriction Plus Plant-based Diet in Cancer Patients Receiving Chemotherapy	N/A