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Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone

Medical; Abortion, Fetus Clinical Trial

Official title:
Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone in First Trimester Pregnancy

Clinical Trial Summary

Comparison of rate of complete abortion between Letrozole plus Misoprostol versus Misoprostol alone in first trimester pregnancy

Clinical Trial Description

Comparison of rate of complete abortion between Letrozole plus Misoprostol versus Misoprostol alone in first trimester pregnancy; RCT This reseach focus on the medical abortion in the early pregnancy loss. The target population is 70 patients (35 per group). We devide patient into 2 groups, intervention and control group. In intervention group we give the Letrozole 10 mg PO daily at day 1-3 prior to Misoprostol 800 mcg SL in day 4. In control group we give only Misoprostol 800 mcg SL. Then, thepatien will follow up on day 7, TVS will be done to diagnose the complete abortion. The primary outcome is rate of complete abortion between 2 groups. The secondary outcome is side effect of letrozole and induced to abortion time. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05940233
Study type Interventional
Source Queen Savang Vadhana Memorial Hospital, Thailand
Contact Sutinee Srimahachota, M.D.
Phone 0847202666
Email srimahachota@gmail.com
Status Recruiting
Phase N/A
Start date June 30, 2023
Completion date May 30, 2025
View Details
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