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Clinical Trial Summary

The aim of this project is therefore to explore on the clinical significance of analyzing surrogate markers combined with conventional diagnostics in the ICU setting. BAL, blood and biopsy samples will be subjected to a combined analysis of GM, BDG, Aspergillus specific PCR assays in addition to conventional diagnostics (Microscopy, Culture,Histology) for ICU pts with pulmonary infiltrates.

As GM and BDG are not species-specific, three established and repeatedly published species specific PCR-based assays (nested PCR, real time PCR assay, multifungal DNA Array)developed by our group will be investigated in combination with the serological tests in a multicenter prospective clinical diagnostic trial.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT01695499
Study type Observational
Source Heidelberg University
Contact
Status Enrolling by invitation
Phase
Start date August 2012
Completion date December 2020

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