Clinical Trials Logo

Clinical Trial Summary

May-Thurner syndrome is the result of compression of the left common iliac vein between the right common iliac artery and overlying vertebrae.

In This Study , We will detect the role of color doppler US in the diagnosis of May-Thurner Syndrome in comparison to Direct CT Venography


Clinical Trial Description

May-Thurner syndrome (MTS) is a venous compression syndrome in which the left common iliac vein is compressed between the lower lumbar spine and the right common iliac artery. While asymptomatic compression is very common, the process can lead to morbidity in selected individuals, most commonly deep venous thrombosis (DVT) and the sequelae thereof. Radiologists must recognize the diagnosis because of the unique management, which differs from DVT without iliac vein compression.

The most common clinical presentation is unilateral leg swelling due to acute DVT. It can also present as chronic venous insufficiency or chronic thrombosis with symptoms of venous hypertension and venous stasis namely claudication, pain, swelling, varicose veins and / or ulceration.

Conventional invasive catheter venography remains the gold standard for diagnosis,but the decision to undertake invasive venography should be made only after reviewing all available clinical data and alternative, less invasive imaging options have been exhausted.

When visualization of the common iliac veins is possible, MTS may be diagnosed with transabdominal color Doppler U/S.

MDCT with IV contrast is a fast, widely available examination for the diagnosis of MTS and accompanying complications .

Magnetic resonance imaging (MRI) with MR venography is an attractive modality for the diagnosis, However, MRI is expensive, time consuming, has more limited availability than computed tomography (CT) and ultrasound, and may be impossible in select patients. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03262987
Study type Observational
Source Assiut University
Contact Omar Mokhtar, M.B.B.CH
Phone +201094584576
Email ogamalm2217@gmail.com
Status Not yet recruiting
Phase N/A
Start date October 1, 2017
Completion date December 30, 2018

See also
  Status Clinical Trial Phase
Completed NCT05076448 - The Efficacy and Safety of Interventions on the Pelvic Veins in Pelvic Venous Disorders
Active, not recruiting NCT04580160 - Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System N/A
Recruiting NCT05628948 - Vascular Lab Resource (VLR) Biorepository
Recruiting NCT04067505 - Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study Phase 3
Completed NCT06180122 - The Use and Reproducibility of Duplex Ultrasound to Provide Indices of Left Common Iliac Vein Diameter N/A
Completed NCT02655887 - BARD® The VENOVO™ Venous Stent Study for Treatment of Iliofemoral Occlusive Disease N/A
Recruiting NCT02584374 - Balloon Test for Iliac Vein Compression N/A
Recruiting NCT02240914 - Vascular Ultrasound Versus Intravascular Ultrasound for Diagnosing Iliac Vein Obstruction N/A
Completed NCT02149212 - Iliac Vein Stenting in Advanced Chronic Venous Insufficiency Phase 4
Completed NCT01846780 - Treadmill Pilot Study (Invasive Pressure Measurements in PTS) N/A
Not yet recruiting NCT05409781 - Prevalence of May-Thurner Syndrome in 1st-degree Relatives of Symptomatic Patients
Completed NCT01206751 - Multi-detector Computer Tomography Protocol Project: Chest Imaging Technique and Case Presentation N/A