May-Thurner Syndrome Clinical Trial
Official title:
Color Doppler U/S vs MSCT Venography in the Diagnosis of May-Thurner Syndrome
May-Thurner syndrome is the result of compression of the left common iliac vein between the
right common iliac artery and overlying vertebrae.
In This Study , We will detect the role of color doppler US in the diagnosis of May-Thurner
Syndrome in comparison to Direct CT Venography
May-Thurner syndrome (MTS) is a venous compression syndrome in which the left common iliac
vein is compressed between the lower lumbar spine and the right common iliac artery. While
asymptomatic compression is very common, the process can lead to morbidity in selected
individuals, most commonly deep venous thrombosis (DVT) and the sequelae thereof.
Radiologists must recognize the diagnosis because of the unique management, which differs
from DVT without iliac vein compression.
The most common clinical presentation is unilateral leg swelling due to acute DVT. It can
also present as chronic venous insufficiency or chronic thrombosis with symptoms of venous
hypertension and venous stasis namely claudication, pain, swelling, varicose veins and / or
ulceration.
Conventional invasive catheter venography remains the gold standard for diagnosis,but the
decision to undertake invasive venography should be made only after reviewing all available
clinical data and alternative, less invasive imaging options have been exhausted.
When visualization of the common iliac veins is possible, MTS may be diagnosed with
transabdominal color Doppler U/S.
MDCT with IV contrast is a fast, widely available examination for the diagnosis of MTS and
accompanying complications .
Magnetic resonance imaging (MRI) with MR venography is an attractive modality for the
diagnosis, However, MRI is expensive, time consuming, has more limited availability than
computed tomography (CT) and ultrasound, and may be impossible in select patients.
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