Maternal Uterine Artery Doppler Study

Maternal-Fetal Exchange Clinical Trial

Official title:

A Simple Technique to Modify Maternal Uterine Artery Perfusion.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01698957
• Other study ID #: UA Doppler 2012
• Status: Completed
• Phase: N/A
• First received: October 1, 2012
• Last updated: November 21, 2016
• Start date: September 2012
• Est. completion date: September 2016

Study information

• Verified date: November 2016
• Source: Mednax Center for Research, Education and Quality
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to detect if adding resistance to maternal blood flow from the arm will help increase the blood flow through the uterine arteries to the placenta and the baby.

Description:

In the setting of uteroplacental insufficiency, there is little that can be done to increase blood flow through the uterus and placenta. Historically, women with growth restricted fetuses or oligohydramnios have been placed on bed rest. Unfortunately, this treatment modality has met with only limited success. Cardiologists have long recognized the simple act of making a fist or otherwise occluding blood flow through a limb dramatically increases a person's peripheral vascular resistance. If maternal peripheral resistance can be increased, perhaps the increased differential between the maternal peripheral vascular resistance and that of the uteroplacental unit will increase flow through the uterus and placenta.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 52
• Est. completion date: September 2016
• Est. primary completion date: August 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Pregnant women greater than or equal to 18 years old

• Able to speak and read English

• Have a singleton pregnancy greater than or equal to 18 weeks gestation

Exclusion Criteria:

• Multiple gestation

• Less than 18 weeks gestation

• Uterine anomalies

• Fetal anomalies

• Preeclampsia

• Hypertension

• Inability to have BP cuff on left arm

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Maternal-Fetal Exchange

Intervention

Other:
• Any patient eligible for an Ultrasound greater than or equal to 18 weeks gestation without a fetal or uterine anomaly.
bilateral Uterine artery Doppler readings pre- and during blood pressure measurement

Locations

Country	Name	City	State
United States	Phoenix Perinatal Associates	Glendale	Arizona
United States	Phoenix Perinatal Associates	Phoenix	Arizona

Sponsors (1)

Lead Sponsor	Collaborator
Obstetrix Medical Group

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Uterine Artery Doppler	The purpose of this study is to detect if adding resistance to maternal blood flow from the arm will help increase the blood flow through the uterine arteries to the placenta and the baby.	at time of routine ultrasound	No