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Efficiency of Manual Therapy on Central Sensitization in Patients With Nonspecific Chronic Back Pain

Manual Therapy Clinical Trial

Official title:
Efficiency of Manual Therapy on Central Sensitization in Patients With Nonspecific Chronic Back Pain.A Randomized Controlled Study.

Clinical Trial Summary

Central sensitization (CS) is defined as the increased responsiveness of nociceptive neurons in the central nervous system to normal or subthreshold afferent input. CS has been proposed as an underlying mechanism of chronic pain in musculoskeletal disorders including low back pain (LBP). The aim of this study is to investigate the effect of manual therapy on central sensitization in patients with nonspecific chronic LBP.

Clinical Trial Description

A total of 40 LBP patients aged between 24-64 with CSS will be randomized into two groups. The manual therapy group will receive a 4-week manual therapy (two sessions/week) plus the conventional physiotherapy program, while the control group will only receive conventional physiotherapy. Before and after the interventions pain intensity (VAS), and scores of three questionnaires: Oswestry Disability Index (ODI), Central Sensitization Inventory (CSI), and the 36-item Short Form Health Survey Questionnaire (SF-36) will be recorded.The outcomes of the study will be analyzed by appropriate statistical methods. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05937503
Study type Interventional
Source Atilim University
Contact
Status Not yet recruiting
Phase N/A
Start date July 17, 2023
Completion date August 30, 2023
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