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Clinical Trial Summary

This is a prospective, single arm, open-label, exploratory study in women with primary operable HER2-positive, HER2-enriched(HER2-E)/ERBB2-high breast cancer according to PAM50 intrinsic subtype and a ERBB2 pre-defined cutoff (high vs low ERBB2 expression), to evaluate the omission of surgery and sentinel lymph node dissection in patients with HER2-E and ERBB2 high breast cancer who achieving a complete response following standard anti-HER2-based neoadjuvant therapy with paclitaxel/trastuzumab/pertuzumab.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04301375
Study type Interventional
Source Hospital Clinic of Barcelona
Contact Nuria Chic, MD
Email CHIC@clinic.cat
Status Not yet recruiting
Phase Phase 2
Start date June 15, 2020
Completion date July 15, 2027

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