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Clinical Trial Summary

This is a prospective, single arm, phase II trial in previously treated patients with MPM who are considered candidates for immunotherapy and repeat thoracoscopies/transthoracic biopsies. Nivolumab will be administered 3 mg/kg q2 weeks by intravenous injection.

The administration of nivolumab as monotherapy will improve DCR form 20% to 40% at 12 weeks when compared to DCR of patients treated with best supportive care based on historical controls.


Clinical Trial Description

Patients will undergo pre- and post-treatment thoracoscopies/biopsies. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02497508
Study type Interventional
Source The Netherlands Cancer Institute
Contact
Status Completed
Phase Phase 2
Start date July 2015
Completion date July 2017

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