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ICSI Versus Conventional IVF in Couples With Non-severe Male Infertility — ICSI/IVF-NSMI  

Male Infertility Clinical Trial

Official title:
Intracytoplasmic Sperm Injection (ICSI) Versus Conventional in Vitro Fertilization (IVF) in Couples With Non-severe Male Infertility: a Randomized Controlled Trial

Clinical Trial Summary

A multicenter, parallel-controlled(1:1 treatment ratio), open-label, randomized clinical trials regarding fertilization and pregnancy outcomes between ICSI and conventional IVF among couples with no-severe male-factor infertility in China.

Clinical Trial Description

A multicenter, large-scale, randomized controlled clinical trial will enroll 2,346 couples with non-severe male infertility undergoing their first or second cycle of IVF or ICSI. The study will recruit participants from 6 Reproductive Medical Centers across mainland China.The participation in this study will be approximately 2 years with a total of 7 visits from controlled ovarian hyperstimulation, pregnancy to delivery. On the day of oocyte retrieval, eligible participants will be allocated to two groups at a ratio of 1:1- ICSI protocol, and conventional IVF protocol. All participants will be randomized through stratified block randomization according to the study sites. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03298633
Study type Interventional
Source Peking University Third Hospital
Contact
Status Completed
Phase N/A
Start date April 4, 2018
Completion date March 31, 2023
View Details
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