Malaria Clinical Trial
Official title:
Effectiveness of Nutritional Supplementation (RUTF and Multi Micronutrient) in Preventing Malnutrition in Children 6-59 Months With Infection (Malaria, Pneumonia, Diarrhoea), a Randomized Controlled Trial in Nigeria
The purpose of this study is to determine whether 14 days nutritional supplementation with Ready to use therapeutic Food (RUTF) or micronutrients alone to children having an infection will prevent malnutrition and reduce the frequency of morbidity.
Anorexia due to infection might lead to weight loss. In many settings total recovery is
problematic what might result in a permanent lower weight. A short period high quality food
supplementation could improve weight gain after an infection.
A complete high quality food will be tested, but also micronutrients alone as there is no
information on what children with an infection exactly need as a supplement.
Children aged 6-59 months presenting with diarrhoea, malaria or lower respiratory tract
infection (LRTI) are provided for 2 weeks with
- RUTF supplement (Plumpynut®) of 500 kcal/day
- Multi-micronutrient powder (MNP)
- Placebo to MNP
The followup period is 6 months. Anthropometric indicators and morbidity are assessed
monthly. Participants are invited to attend the study clinic if any signs of disease are
noticed.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Prevention
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