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MSP3-CRM-Vac4All/ Alhydrogel® Malaria Vaccine — MSP3CRMV4All  

Malaria,Falciparum Clinical Trial

Official title:
Phase 1 Randomized, Dose-finding Study to Evaluate the Safety, Tolerability and Immunogenicity of a Novel Malaria Vaccine, MSP3-CRM-Vac4All/ Alhydrogel®, in Healthy Adults

Clinical Trial Summary

First-in-Human, Randomised, Dose-Finding Single Center Study to evaluate three dose levels of a novel malaria vaccine, MSP3-CRM-Vac4All/ Alhydrogel® : 3 µg, 10 µg and 30 µg

Clinical Trial Description

A total of 42 healthy male and female participants aged 18 to 55 years will be enrolled and randomized into one of three cohorts. Three dose levels of a novel malaria vaccine, MSP3-CRM-Vac4All/ Alhydrogel®, will be evaluated: 3 µg, 10 µg and 30 µg total MSP3-CRM197 conjugate protein (corresponding to 1, 3, 10 µg MSP3 protein) administered as a primary series of three intramuscular (IM) injections, given on day 1, day 28, and day 56. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05197751
Study type Interventional
Source Vac4All
Contact
Status Active, not recruiting
Phase Phase 1
Start date December 1, 2021
Completion date May 9, 2023
View Details
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