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Intravenous Oliceridine and Opioid-related Complications

Major Surgery Clinical Trial

Official title:
Intravenous Oliceridine and Opioid-related Complications: VOLITION: A Multicenter Pilot Cohort Study

Clinical Trial Summary

The investigator will evaluate the side effects of oliceridine.

Clinical Trial Description

The investigator will evaluate the side effects of oliceridine. Limited information suggests that oliceridine may cause fewer side effects than the standard opioids given post surgery. Oliceridine is effective for treating acute pain, and is approved by the FDA. Patients will wear a device that continuously monitors breathing. Data from this monitor will be blinded to the clinical staff. Primary Aims include: The investigators will evaluate the proportion of patients having an adjudicated meaningful respiratory compromise with a specified precision of 0.15 using a 95% confidence interval at 24 hours post first study dose. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04979247
Study type Interventional
Source The Cleveland Clinic
Contact Roberta Johnson
Phone 216-444-9950
Email johnsor13@ccf.org
Status Recruiting
Phase Phase 4
Start date September 15, 2021
Completion date July 15, 2025
View Details
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