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Clinical Trial Summary

Some patients participating in the underlying GUARDIAN trial (NCT04884802) will be additionally randomized to etomidate vs propofol for anesthetic induction.


Clinical Trial Description

Patients participating in the underlying GUARDIAN trial (NCT04884802) will be randomized to: 1) routine intraoperative blood pressure management (routine pressure management); or 2) norepinephrine or phenylephrine infusion to maintain intraoperative MAP ≥85 mmHg (tight pressure management). Patients participating in this sub-study will be additionally randomized to etomidate or propofol for induction of anesthesia. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04934683
Study type Interventional
Source The Cleveland Clinic
Contact Fabio Rodriquez Patarroyo, MD
Phone 216) 444-9674?
Email Rodrigf3@ccf.org
Status Recruiting
Phase Phase 3
Start date July 27, 2021
Completion date July 2025

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