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Major Depressive Disorder clinical trials

View clinical trials related to Major Depressive Disorder.

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NCT ID: NCT01380704 Completed - Clinical trials for Major Depressive Disorder

Safety and Pharmacodynamic Study of ABT-436 in Major Depressive Disorder

Start date: June 2011
Phase: Phase 1
Study type: Interventional

This is a multiple-dose study to assess the safety and pharmacology of ABT-436 in physically healthy subjects with mild to moderate depressive symptoms who are not taking any antidepressant medication. Efficacy for treatment of depressive symptoms is not a goal of this study.

NCT ID: NCT01380691 Completed - Clinical trials for Major Depressive Disorder

A Study of LY2216684 in Healthy Participants

Start date: June 2011
Phase: Phase 1
Study type: Interventional

This study will evaluate the pharmacodynamic and pharmacokinetic interaction of LY2216684 with alcohol in healthy participants. This study will run approximately for 34 days.

NCT ID: NCT01377194 Completed - Clinical trials for Major Depressive Disorder

Safety and Efficacy of Levomilnacipran ER (Levomilnacipran SR) in Major Depressive Disorder

Start date: June 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, and tolerability of Levomilnacipran ER compared to placebo in patients with Major Depressive Disorder (MDD).

NCT ID: NCT01372150 Completed - Clinical trials for Major Depressive Disorder

A Study Of DVS SR In Treatment Of Children And Adolescent Outpatients With MDD

Start date: November 17, 2011
Phase: Phase 3
Study type: Interventional

This is a Double-blind Study Evaluating Desvenlafaxine Succinate (DVS SR) Sustained Release vs Placebo in the Treatment of Children and Adolescent Outpatients with Major Depressive Disorder (MDD).

NCT ID: NCT01371734 Completed - Clinical trials for Major Depressive Disorder

A Study Of DVS SR In Treatment Of Children And Adolescent Outpatients With MDD

Start date: August 2011
Phase: Phase 3
Study type: Interventional

This is a double-blind study evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) versus placebo in the Treatment of Children and Adolescent Outpatients with Major Depressive Disorder (MDD).

NCT ID: NCT01371721 Completed - Clinical trials for Major Depressive Disorder

A 6-Month Open-Label Extension Study to the B2061014 Study to Evaluate the Safety, Tolerability and Efficacy of DVS SR in the Treatment of Children and Adolescents With MDD

Start date: February 2012
Phase: Phase 3
Study type: Interventional

This is a 6-month, open-label, flexible-dose study evaluating desvenlafaxine succinate sustained release (DVS SR) in the treatment of child and adolescent outpatients with major depressive disorder (MDD).

NCT ID: NCT01371708 Completed - Clinical trials for Major Depressive Disorder

A 6-Month Extension Study To The B2061032 Study To Evaluate The Safety, Tolerability, And Efficacy Of DVS SR In The Treatment Of Child And Adolescent Outpatients With MDD

Start date: February 2012
Phase: Phase 3
Study type: Interventional

This is a 6-month, open-label, flexible-dose study evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) in the Treatment of Child and Adolescent Outpatients with Major Depressive Disorder (MDD).

NCT ID: NCT01370733 Completed - Clinical trials for Major Depressive Disorder

Synchronized Transcranial Magnetic Stimulation (sTMS) in Major Depressive Disorder

NEST-MDD
Start date: May 2012
Phase: Phase 3
Study type: Interventional

This study is designed to evaluate the safety and efficacy of synchronized transcranial magnetic stimulation (sTMS) using the NeoSync EEG Synchronized TMS device (NEST) in subjects with Major Depressive Disorder. This is a multicenter study in which subjects will be randomized to receive treatment 5 days per week for 6 weeks. Subjects who complete 6 weeks of double-blind treatment may be eligible to receive up to four weeks of open label sTMS therapy or antidepressant medications during the follow-up phase of the study. Follow-up evaluation visits will be conducted during those four weeks, with the frequency of the visits determined by the treatment choice during that timeframe.

NCT ID: NCT01370499 Completed - Clinical trials for Major Depressive Disorder

A Study of LY2216684 in Participants With Major Depression Disorder

Start date: August 2011
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the long-term safety and tolerability of LY2216684 administered once daily in the adjunctive treatment with an Selective Serotonin Reuptake Inhibitors (SSRI) for up to approximately 1 year in participants with Major Depressive Disorder (MDD) who were partial responders to their SSRI treatment.

NCT ID: NCT01369030 Completed - Clinical trials for Major Depressive Disorder

Deplin® P.L.U.S. Program (Progress Through Learning Understanding & Support)

Start date: November 2010
Phase: N/A
Study type: Observational

This study will be an observational study in which patients who have been prescribed Deplin® are invited to participate in surveys regarding their experiences with Deplin®. The purpose of this study is to increase the understanding of the role of L-methylfolate among patients who are candidates for Deplin®, provide patients with personalized education and support, and contribute to the overall understanding of the needs and concerns of patients being treated for depression.