Lymphoma Clinical Trial
Official title:
Dapsone Induced Methemoglobinemia in Pediatric Hematologic Malignancy and Aplastic Anemia
RATIONALE: Gathering information about how often methemoglobinemia occurs in young patients
receiving dapsone for hematologic cancer or aplastic anemia may help doctors learn more
about the disease and plan the best treatment.
PURPOSE: This research study is looking at methemoglobinemia in young patients with
hematologic cancer or aplastic anemia treated with dapsone.
OBJECTIVES:
- Define the incidence of methemoglobinemia in patients with hematologic malignancy or
aplastic anemia who received dapsone prophylaxis through a retrospective chart review
encompassing the last 15 years.
- Identify major risk factors for developing methemoglobinemia.
OUTLINE: Medical charts are reviewed. Of particular interest is demographic information,
reasons for beginning dapsone prophylaxis, duration of dapsone prophylaxis, dapsone dosing,
methemoglobin level, and treatment with methylene blue.
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