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Lymphoma clinical trials

View clinical trials related to Lymphoma.

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NCT ID: NCT03357627 Completed - Clinical trials for Lymphoma, Non-Hodgkin

A Study of TAK-659 in Combination With Venetoclax for Adult Participants With Previously Treated Non-Hodgkin Lymphoma

Start date: February 16, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) of TAK-659 and venetoclax when administered in combination in participants with non-Hodgkin lymphoma (NHL) relapsed and/or refractory after at least 1 prior line of therapy and to evaluate safety and tolerability of TAK-659 and venetoclax when administered in combination.

NCT ID: NCT03356678 Completed - Clinical trials for Relapsed or Refractory Peripheral T-cell Lymphoma

Pralatrexate for Relapsed or Refractory Peripheral T-cell Lymphoma

Start date: September 23, 2016
Phase: N/A
Study type: Observational

A non-interventional, multicenter, multinational retrospective analysis using electronic case report forms completed by the investigators based on information from patient medical records

NCT ID: NCT03349450 Completed - Recurrent Clinical Trials

DPX-Survivac and Checkpoint Inhibitor in DLBCL

SPiReL
Start date: March 13, 2018
Phase: Phase 2
Study type: Interventional

This is a Phase 2 non-randomized, open label, uncontrolled, efficacy and safety study. Study participants will receive two priming doses of 0.5mL of DPX-Survivac 21 days apart and up to six 0.1ml maintenance injections every two months with low dose metronomic oral cyclophosphamide (50 mg BID) for one year or until disease progression, whichever occurs first. Pembrolizumab 200 mg will be administered every 3 weeks for up to one year or until disease progression, whichever occurs first.

NCT ID: NCT03349333 Completed - Clinical trials for Relapsed T-Cell Lymphoma

A Single Arm Study Evaluating the Efficacy and Safety of Pralatrexate in Subjects With Relapsed or Refractory PTCL

Start date: September 10, 2015
Phase: Phase 3
Study type: Interventional

This is a single arm, open-label, multi-center study designed to demonstrate the efficacy and safety of pralatrexate when administered concurrently with vitamin B12 and folic acid supplementation to patients with relapsed or refractory peripheral T-cell lymphoma(PTCL).

NCT ID: NCT03343665 Completed - Hodgkin Lymphoma Clinical Trials

Treatment With Nivolumab at the Fixed Dose 40 mg (Nivo40) in Patients With Relapsed/Refractory Hodgkins Lymphoma

Nivo40
Start date: August 1, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

A phase I/II trial to evaluate the safety and efficacy of nivolumab at the fixed dose 40 mg in patients with relapsed or refractory Hodgkins lymphoma.

NCT ID: NCT03343652 Completed - Hodgkin's Lymphoma Clinical Trials

A Study of Safety and Efficacy of Nivolumab and Bendamustine (NB) in Patients With Relapsed/Refractory Hodgkin's Lymphoma

NB001
Start date: May 27, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

A clinical study of safety and efficacy of treatment with Nivolumab and Bendamustine (NB) in patients with relapsed/refractory Hodgkin's lymphoma.

NCT ID: NCT03342586 Completed - Clinical trials for Central Nervous System Lymphoma

Using a Novel Functional MRI Technique to Evaluate for Neurotoxicity

Start date: November 7, 2017
Phase:
Study type: Observational

The purpose of this study is to test resting state functional Magnetic Resonance Imaging (rsfMRI) scans to see if rsfMRI scans are better than the standard task based fMRI scans at diagnosing or monitoring central nervous system lymphoma.

NCT ID: NCT03340766 Completed - Clinical trials for Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)

Study Investigating the Safety and Efficacy of Blinatumomab in Combination With Pembrolizumab in Adults With Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)

HARBOUR
Start date: March 16, 2018
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to determine the maximum tolerated dose (MTD) of blinatumomab in combination with pembrolizumab in adults with relapsed or refractory (r/r) DLBCL.

NCT ID: NCT03336138 Completed - Lymphoma Clinical Trials

Application of Telemedicine to the Management of Aggressive Lymphomas

AMA
Start date: January 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the value of AMA in a comparative multicenter regional study as a reference for aggressive lymphoma. The primary endpoint will be RDI. This study consider that the AMA support should allow a significant improvement of the RDI compared to the control group and thus impact the duration without progression. The study covers 350 patients recruited from 10 regional centers.

NCT ID: NCT03332121 Completed - Clinical trials for CD20 Positive B Cell Non-Hodgkin's Lymphoma

B001 in Patients With CD20 Positive B-cell Non Hodgkin's Lymphoma

Start date: March 22, 2018
Phase: Phase 1
Study type: Interventional

It's the first-in-human study of Recombinant Humanized Anti-CD20 Monoclonal Antibody for Injection (B001). The main purpose of this study is to explore the safety and tolerance of B001 for patients with CD20 positive B-cell non Hodgkin's lymphoma. It will also explore the PK/PD manner and ORR in this study.