Lymphoma, Non-Hodgkin's Clinical Trial
Official title:
PNT2258-02: A Pilot Phase II Study of PNT2258 for Treatment of Relapsed or Refractory Non-Hodgkin's Lymphoma
This study is sponsored by Sierra Oncology, Inc. formerly ProNAi Therapeutics, Inc. It study is a multi-center, nonrandomized, open-label, pilot Phase II investigation of PNT2258 to characterize anti-tumor activity and collect safety data on patients with relapsed or refractory lymphoma.
PNT2258 will be administered at a dose of 120 mg/m2, as a 3-hour intravenous (IV) infusion on days 1-5 of a 21-day cycle. Treatment may continue (unless there is disease progression or the occurrence of unacceptable toxicity) for a total of 6 cycles of therapy. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
NCT00363636 -
A Study of Galiximab + Rituximab Versus Rituximab + Placebo in Follicular Non-Hodgkin's Lymphoma (NHL)
|
Phase 3 | |
Terminated |
NCT00594308 -
In-Vivo Activated T-Cell Depletion to Prevent GVHD
|
N/A | |
Terminated |
NCT02518750 -
Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma
|
Phase 2 | |
Terminated |
NCT00384150 -
Retreatment Study of Galiximab + Rituximab in Follicular Non-Hodgkin's Lymphoma (NHL)
|
Phase 3 | |
Terminated |
NCT00141700 -
Study of Rituximab Plus High-Dose Chemotherapy Poor Prognosis Non-Hodgkin's Lymphoma
|
Phase 2 | |
Terminated |
NCT00143884 -
Study of Low Intensity Conditioning and Immunotherapy for High-Risk Cancers of the Blood
|
Phase 2 | |
Completed |
NCT02750670 -
Obinutuzumab in Combination With GDP Chemotherapy in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
|
Phase 2 | |
Terminated |
NCT02473523 -
Yoga to Alleviate Fatigue, Anxiety and Pain in Adolescents During Treatment for Lymphoma or Leukemia
|
N/A | |
Completed |
NCT00413036 -
A Study of Revlimid in the Treatment of Non-Hodgkin's Lymphoma
|
Phase 2 | |
Completed |
NCT00161590 -
Study of CHOP + Campath for T-Cell, Null Cell, or Natural Killer (NK)-Cell Lymphoma
|
Phase 1 | |
Terminated |
NCT00651443 -
Mechanism of Action of Galiximab in Subjects With Previously Untreated Follicular Non-Hodgkin's Lymphoma
|
Phase 1 | |
Recruiting |
NCT04756726 -
Study to Assess the Safety and Tolerability of CFT7455 in Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma
|
Phase 1/Phase 2 | |
Terminated |
NCT00395967 -
AMD3100 (Plerixafor) in Multiple Myeloma (MM) or Non-Hodgkin's Lymphoma (NHL) Patients Predicted to be Unable to Mobilize With G-CSF Alone
|
Phase 2 | |
Completed |
NCT00143871 -
Study of Rituximab Plus High-Dose Chemotherapy Non-Hodgkin's Lymphoma
|
Phase 2 |