Lymphocytic Leukemia, Chronic Clinical Trial
Official title:
Feasibility/Phase II Trial of Fludarabine, Rituximab, and Alemtuzumab for Previously Treated B-Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)
Verified date | February 2017 |
Source | Ohio State University Comprehensive Cancer Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This purpose of this study is to assess the toxicity and the rate of complete and overall response using fludarabine, rituximab, and alemtuzumab to treat patients with B-chronic lymphocytic leukemia or small lymphocytic leukemia who have received previous treatment.
Status | Completed |
Enrollment | 8 |
Est. completion date | July 2009 |
Est. primary completion date | February 2007 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Must have B-CLL/SLL - active disease - >=1 prior systemic therapy - ECOG PS 0-2. Exclusion Criteria: - Pregnant or nursing women |
Country | Name | City | State |
---|---|---|---|
United States | Ohio State University | Columbus | Ohio |
Lead Sponsor | Collaborator |
---|---|
Ohio State University Comprehensive Cancer Center |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Assess the rate of complete (CR) and overall response (ORR) using fludarabine, rituximab, and alemtuzumab | 2005-present | ||
Secondary | Assess toxicity of this regimen. | 2005-present |
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