Lymph Node Metastases Clinical Trial
Official title:
Prospective Study for the Dissection of Lymph Node Posterior to Right Recurrent Laryngeal Nerve for Papillary Thyroid Carcinoma
This study was completed in two stages. In the first stage, 2000 participants were enrolled
according to the criteria. Following the principle of informed consent and voluntary consent
of patients, the standard operation was "right or bilateral thyroidectomy + isthmus resection
+ right area VI lymph node dissection + left area VI lymph node dissection + lateral neck
lymph node dissection". The age of participants, the size of right thyroid tumors, the
invasion of the capsule and the number of lateral neck lymph node metastasis were counted to
validate and improve the predictive model of lymph node posterior to the right recurrent
laryngeal nerve in papillary thyroid cancer (Y=−0.029×age+0.771×tumor size+0.660×capsular
invasion+1.331×right lateral lymph node metastasis−1.687, Y ≥0.16 means right recurrent
laryngeal nerve posterior lymph node metastasis).
In the second stage, 2000 participants assessed by the model without posterior right
recurrent laryngeal nerve metastasis were randomly divided into experimental group and
control group according to the principle of informed consent and voluntary. The right
recurrent laryngeal nerve posterior lymph nodes were not dissected in experimental group,
while the right recurrent laryngeal nerve posterior lymph nodes were routinely dissected in
control group. Through long-term follow-up and comparison of RFS and OS between the two
groups, the investigators can scientifically evaluate the effectiveness of the "prediction
model of lymph node posterior to right recurrent laryngeal nerve metastasis in papillary
thyroid carcinoma", and seek evidence for accurate treatment of lymph node posterior to the
right recurrent laryngeal nerve in thyroid papillary carcinoma.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03280719 -
Whole Breast + Lymph Node Irradiation: Prone Compared to Supine Position in 15 or 5 Fractions
|
N/A | |
| Active, not recruiting |
NCT04300673 -
Radio Guided Lymph Node Dissection in Oligometastatic Prostate Cancer Patients
|
Phase 1/Phase 2 | |
| Completed |
NCT04260139 -
Lymph Node Yield in Colon Cancer Resection Specimens
|
||
| Not yet recruiting |
NCT03632746 -
Verifying the Specificity of a New Method in Predicting Lymph Node Metastasis in Early Gastric Cancer Patients
|
||
| Active, not recruiting |
NCT03776591 -
Open D3 Right Hemicolectomy Compared to Laparoscopic CME for Right Sided Colon Cancer
|
N/A | |
| Recruiting |
NCT05078853 -
Thyroglobulin Point of Care Assay for Rapid Detection of Metastatic Differentiated Thyroid Carcinoma
|
||
| Recruiting |
NCT03715686 -
To Accurately Assess Lymph Node Response to NACT by Wire Localization of Clip-marked Lymph Nodes
|
N/A | |
| Recruiting |
NCT03280134 -
A Prospective Validation Cohort Study of a Prediction System on nSLN Metastasis in Early Breast Cancer
|
N/A | |
| Recruiting |
NCT04117139 -
The Diagnostic Value of PET/MRI in Head and Neck Cancer
|
N/A | |
| Recruiting |
NCT04882618 -
Use of Indocyanine Green During Pelvic Lymph Node Dissection in Prostate Cancer.
|
Phase 4 | |
| Recruiting |
NCT05670574 -
Surgery With Extended (D3) Mesenterectomy for Small Bowel Tumors
|
N/A | |
| Active, not recruiting |
NCT04611997 -
IGG Using in Laparoscopic Gastrectomy for Locally Advanced Gastric Cancer After Neoadjuvant Chemotherapy
|
Phase 3 | |
| Recruiting |
NCT04744506 -
Targeted Resection of Axillary Metastatic Lymph Nodes After Breast Cancer Neoadjuvant Chemotherapy
|
N/A | |
| Recruiting |
NCT03830242 -
Diagnostic Significance of FDG PET/CT Dynamic Imaging in Detecting Metastatic Lymph Nodes With Papillary Thyroid Cancer.
|
N/A | |
| Recruiting |
NCT04959604 -
Lymph Node Mapping Via Flourescent Dye in Colon Cancer
|
N/A | |
| Active, not recruiting |
NCT04419935 -
Lymphadenectomy in NSCLC With and Without Adjuvant Therapy
|
||
| Enrolling by invitation |
NCT04322331 -
Tumor Immune Mechanism of Axillary Lymph Node Metastasis in Early Luminal Type A Breast Cancer
|
||
| Recruiting |
NCT03868215 -
Use of Plasma ctDNA Methylation Haplotypes in Detecting Local Residual or Lymph Node Metastasis
|
||
| Recruiting |
NCT04337333 -
Two-in-one Covered and Uncovered Metal Stent
|
N/A | |
| Completed |
NCT04068636 -
Sentinel Node in Larynx and Pharynx Cancers
|
N/A |