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NCT00558597 Clinical Trial

Proteomics Analysis for Recognition of Acute Cellular Rejection After Lung Transplantation

Lung Transplantation Clinical Trial

Official title:
Proteomics Analysis for Recognition of Acute Cellular Rejection After Lung Transplantation

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00558597
Other study ID # 154
Secondary ID
Status Recruiting
Phase N/A
First received November 14, 2007
Last updated July 19, 2011
Start date March 2008
Est. completion date December 2011

Study information
Verified date September 2008
Source Hannover Medical School
Contact Jens Gottlieb, Dr. med.
Phone +49-511-5320
Email gottlieb.jens@mh-hannover.de
Is FDA regulated No
Health authority Germany: Ethics Commission
Study type Observational

Clinical Trial Summary

In patients with acute rejection after lung transplantation the peptide profile in broncho-alveolar lavage (BAL) and urine should be compared in order to identify a paradigm that allows an non-invasive rejection therapy.

Description:

Goal of the study is the establishment of biomarkers for early diagnosis of acute rejection, followed by a late validation of the paradigm with prospectively collected samples, which will be examined blinded.

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date December 2011
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria:

- Patients with stable graft function

- Patients with acute rejection

Exclusion Criteria:

- Acute infection

- BOS

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Germany Hannover Medical School Hannover

Sponsors (1)
Lead Sponsor Collaborator
Hannover Medical School

Country where clinical trial is conducted

Germany, 

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