Lung Injury Clinical Trial
Official title:
Effect of Variable Volume Ventilation on Lung Compliance During Mechanical Ventilation.
Randomized controlled trial comparing low inspiratory and expiratory flow during variable volume ventilation with a constant volume decelerating flow (pressure controlled volume guarantee) ventilation.
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | December 2022 |
Est. primary completion date | December 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - laparoscopic bariatric surgery requiring mechanical ventilation Exclusion Criteria: - lung disease requiring oxygen before anesthesia - emergence procedure - spontaneous or assisted ventilation |
Country | Name | City | State |
---|---|---|---|
Belgium | Azsintjan | Brugge |
Lead Sponsor | Collaborator |
---|---|
AZ Sint-Jan AV |
Belgium,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of lung recruitments required to keep dynamic lung compliance above 40. | Measuring dynamic lung compliance during mechanical ventilation. When it drops below 40 a lung recruitment is done with increase of PEEP to maximum 15 cmH2O. | during mechanical ventilation under general anesthesia between 1 and 3 hours. No outcome measurements are measured after 3 hours. | |
Secondary | Oxygen saturation at arrival of PACU without oxygen therapy. | oxygen saturation on arrival of PACU without giving oxygen I measured and compared between both groups | during stay in PACU being between 1 and 4 hours post operative of the same day. No outcome measurements are measured after 4 hours. |
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