Lung Injury Clinical Trial
Official title:
Safety and Efficacy of Human Umbilical-Cord-derived Mesenchymal Stem Cell Transplantation in Paraquat Poisoning Induced Lung Injury
Phase I-II Clinical Trial-Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with paraquat poisoning induced lung injury, randomized,single blind, controlled prospective study.
Phase I-II Clinical Trial-Safety and efficacy of umbilical-cord-derived mesenchymal stem
cell (UC-MSC) in patients with paraquat poisoning induced lung injury,randomized, single
blind, controlled prospective study.
Forty patients will be selected and randomized into two groups: the first group of 20
patients will receive three-time injection of UC-MSC and the remaining 20 patients will
comprise the control group.
Every patient will maintain their standard treatment of paraquat poisoning, with maximum
tolerated dosage without side effects.
The day of last infusion will be considered day zero. From that moment, followup will be
divided into 2 d,7 d,14 d, 28 d and 2 m.
Clinical results will be analyzed after completion of 2 months of followup.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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