Lung Cancer Clinical Trial
Official title:
Effect of Muscle and Skin Fixation of Thoracic Drainage Tube on Postoperative Pain in Patients Undergoing Uniport Thoracoscopic Pulmonary Resection
NCT number | NCT05202249 |
Other study ID # | Kli4 |
Secondary ID | |
Status | Recruiting |
Phase | N/A |
First received | |
Last updated | |
Start date | November 15, 2021 |
Est. completion date | May 15, 2022 |
Lung cancer is the leading cause of cancer-related death worldwide. Thoracoscopic pulmonary resection is a prevalent management for early stage of lung cancer. Placement of chest tube is the standard procedure after surgery, which causes pain that cannot be ignored. The investigators aimed to determine whether a muscle layer fixation of thoracic drainage tube could release postoperative pain in patients with uniport thoracoscopic pulmonary resection compared with conventional skin fixation.
Status | Recruiting |
Enrollment | 60 |
Est. completion date | May 15, 2022 |
Est. primary completion date | March 15, 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: - 18<age<80; - ASA=III - Patients with no clinically significant cardiac history, such as ischaemic heart disease, valvular heart disease, rhythm disturbances such as frequent atrial fibrillation or premature ventricular contractions (PVCs). Patients with significant cardiac history should be optimized according the relevant guidelines before surgery is considered. - Normal cardiopulmonary function [predicted forced expiratory volume in the first second(FEV1%) >50% and ejection fraction (EF) >50%of predicted value]. Resting blood gas analysis showing arterial partial pressure of oxygen (PaO2)=75 mmHg and arterial partial pressure of carbon dioxide (PaCO2) <45 mmHg; Exclusion Criteria: - History of ipsilateral surgery and other conditions which can result in extensive pleural adhesion; - Coagulopathy, hypoxemia (PaO2 <60 mmHg), hypercapnia [arterial carbon dioxide tension(PaCO2) >50 mmHg]; - Significant cardiac history. |
Country | Name | City | State |
---|---|---|---|
China | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | Chongqing | Chongqing |
Lead Sponsor | Collaborator |
---|---|
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Postoperative Pain | The postoperative pain is assessed using a Visual Analog Scale (VAS) | From date of operation until the date of chest tube removal, assessed up to 7 days | |
Primary | Pain-associated inflammatory factor | the level of pain-associated inflammatory factor in blood, including CRP, PCT, IL6 and TNFa | the first day after surgery | |
Primary | Dosage of analgesics | Dosage of analgesics | From date of operation until the date of chest tube removal, assessed up to 7 days |
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