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InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Lung Cancer Clinical Trial

Official title:
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk For Cancer

Clinical Trial Summary

This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member who has a family member with a precursor condition for cancer. - The objective of this study is to identify exposures as well as clinical, molecular, and pathological changes that can be used to predict early development of cancer, malignant transformation, and risks of progression to symptomatic cancer that can ultimately be fatal. - The ultimate goal is to identify novel markers of early detection and risk stratification to drive potential therapeutic approaches to intercept progression to cancer.

Clinical Trial Description

The objective of this protocol is to obtain clinical information and facilitate the collection and distribution of specimens obtained during the course of clinical care or research participation. - Blood, buccal swabs, urine or tissue or other body fluids (including stool) may be specifically acquired for research in order to perform molecular and other types of analyses for research purposes. - These materials will be collected from all eligible participants who have a precursor lesion or an increased risk of cancer It is expected that about 5,000 people will take part in this research study. ;

Study Design

Related Conditions & MeSH terms

  • Adenoma
  • Barrett Esophagus
  • Cancer Risk
  • Carcinoma
  • Carcinoma in Situ
  • Carcinoma, Lobular
  • Childhood Cancer Survivors
  • Cirrhosis
  • Endometrial Intraepithelial Neoplasia
  • Fatty Liver
  • Giant Cell Tumors
  • Hematologic Malignancy
  • Hematologic Neoplasms
  • Hyperplasia
  • Liver Diseases
  • Lung Cancer
  • Lung; Node
  • Neoplasms
  • Non Alcoholic Steatohepatitis
  • Non-Alcoholic Fatty Liver Disease
  • Vulvar Intraepithelial Neoplasia
Clinical Trial Details
NCT number NCT05463796
Study type Observational [Patient Registry]
Source Dana-Farber Cancer Institute
Contact Jenna Beckwith, MPH
Phone 857-215-1892
Email inadvancestudy@dfci.harvard.edu
Status Recruiting
Phase
Start date April 25, 2023
Completion date March 25, 2032
View Details
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