Lung Cancer Clinical Trial
Official title:
Study of the Concentration-effect Relationship of Nivolumab in Patients With Kidney or Lung Cancer
To assess the relationship between progression free survival of patients treated with
nivolumab for metastatic non small cell lung carcinoma or a metastatic renal cell carcinoma
and nivolumab blood concentration.
Collection of standard data prospectively.
Nivolumab is a monoclonal antibody used for the treatment of non small cell lung carcinoma
and renal cell carcinoma. Huge variability exists between patients treated by nivolumab in
terms of efficacy and side effects. Like others monoclonal antibodies, a relation between
concentration and effects of nivolumab may exist.
The aim of this study is to assess the relationship between blood concentration of nivolumab
and progression free survival, overall survival and side effects on the one hand, and on the
other to describe pharmacokinetic of nivolumab
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